Special Issue "Halogen Bond: Application and Prospect"
A special issue of Molecules (ISSN 1420-3049).
Deadline for manuscript submissions: closed (31 May 2013)
Weak chemical interactions are of essential importance for life as their cooperative interplay governs the formation of all types of supramolecular organization. They drive self-assembly processes, are responsible for molecular recognition phenomena, and determine the structure of biopolymers and thereby possess a tremendous impact in chemistry and biology. In addition to the four traditionally recognized fundamental secondary interactions, i.e., hydrogen bonding, ionic bonds, hydrophobic interactions and van der Waals forces, halogen bonding is emerging as an additional type of noncovalent bond. The interaction of electropositive halogens with electron donor functionalities is strong, specific and directional. It shows evident similarities to hydrogen bonding, but also distinct differences and is capable of efficiently competing with it. The fact that halogens may form different types of secondary interactions, for example orthogonal halogen and hydrogen bonds, makes them to multifaceted molecular tools. Following its initial studies, the potential of halogen bonding for applicability in a wide variety of scientific fields such as organic, inorganic, physical, biophysical, medicinal and analytical chemistry was demonstrated. The expected future impact of halogen bonding demands a meticulous exploration of its scope and limitations from the experimental and theoretical view points. The objective of this special issue of Molecules is to highlight the last breakthroughs in the exploration and in the applications of halogen bonding, covering all aspects.
Dr. Mate Erdelyi
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed Open Access monthly journal published by MDPI.
- halogen bond
- noncovalent interactions
- drug design
- organic chemistry
- physical organic chemistry
- inorganic chemistry
- medicinal chemistry
- biophysical chemistry
- analytical chemistry