Special Issue "Synthesis, Structure, Analysis and Properties of Glycolipids"
A special issue of Molecules (ISSN 1420-3049).
Deadline for manuscript submissions: closed (20 September 2013)
Prof. Dr. Paul V. Murphy
School of Chemistry, National University of Ireland, Galway, University Road, Galway, Ireland
Interests: synthesis of tumour cell migration & angiogenesis inhibitors; synthesis of peptidomimetics and bioactive compounds based on carbohydrates; synthesis of natural products & mimics; glycoside rearrangements (anomerisation) and applications; glycolipid synthesis; synthesis of spatially defined glycoclusters
Glycolipids are an important class of glycoconjugates. They are comprised of lipids covalently attached to carbohydrates. Important constituents of glycolipids include glycosphingolipids (GSLs), glyceroglycolipids (GGLs) or diacylglycolipids (DAGs), glycosylphosphatidylinositol (GPI anchors) & lipopolysaccharides (LPs). Such glycolipids can have structural roles, or mediate cell-cell interactions including host-pathogen interactions or they can act as antigens. Areas of current scientific interest include the synthesis of the various types of glycolipids, biological evaluation of glycolipids, the determination of structure-activity relationships and analysis of structure of naturally occurring glycolipids. Possible applications include using naturally occurring glycolipids or their mimics as anti-infective agents or as vaccine adjuvants. The objective of this special issue of Molecules is to highlight recent original research in the area of glycolipids.
Prof. Dr. Paul V. Murphy
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed Open Access monthly journal published by MDPI.
- molecular recognition
- cell signalling
- GPI anchor
Article: Synthesis of a-O- and a-S-Glycosphingolipids Related to Sphingomonous cell Wall Antigens Using Anomerisation
Molecules 2013, 18(9), 11198-11218; doi:10.3390/molecules180911198
Received: 31 July 2013; in revised form: 4 September 2013 / Accepted: 5 September 2013 / Published: 12 September 2013| Download PDF Full-text (560 KB)
Molecules 2013, 18(11), 13546-13573; doi:10.3390/molecules181113546
Received: 16 September 2013; in revised form: 15 October 2013 / Accepted: 19 October 2013 / Published: 1 November 2013| Download PDF Full-text (799 KB) | Supplementary Files
Article: Extending the Glucosyl Ceramide Cassette Approach: Application in the Total Synthesis of Ganglioside GalNAc-GM1b
Molecules 2013, 18(12), 15153-15181; doi:10.3390/molecules181215153
Received: 7 November 2013; in revised form: 1 December 2013 / Accepted: 2 December 2013 / Published: 10 December 2013| Download PDF Full-text (610 KB)
Last update: 13 March 2013