Special Issue "Enzyme Chemistry"


A special issue of Molecules (ISSN 1420-3049).

Deadline for manuscript submissions: closed (20 September 2013)

Special Issue Editor

Guest Editor
Dr. Harvey F. Fisher
The Department of Biochemistry, University of Kansas Medical Center, 3901 Rainbow Boulevard, Kansas City, KS 66160, USA
Website: http://www.kumc.edu/school-of-medicine/biochemistry-and-molecular-biology/faculty/harvey-f-fisher-phd.html
E-Mail: hfisher@kumc.edu
Interests: the determination of the chemical mechanism of the glutamate dehydrogenase reaction the energetics of this reaction; the energetics of this reaction; the relationship of the observed energetics to the resolved mechanistic features

Special Issue Information

Dear Colleagues,

Frank Westheimer once proclaimed that it is as if “mother nature has provided us with enzymes as a tool to teach physical-organic chemistry to scientists”. Thus far we have mastered only a minute part of her course. Our purpose in this special issue is to mark our current state in this endeavor. While our focus will be centered on the chemistry of the phenomenon, we will interpret that viewpoint quite broadly. A second objective of this issue is to take advantage ocf the ease of access to a broad audience provided by this journal’s policy and thus provide our colleagues a in related fields with a view of the various experimental and theoretical approaches available to today’s enzyme chemists.

Dr. Harvey F. Fisher
Guest Editor


Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed Open Access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs).


  • intermediate complexes
  • structure-function relationships
  • energetics
  • steady and transient state kinetics
  • kinetic isotope effects
  • chemical bond formation
  • allosteric effects
  • single molecule reactions
  • quantum tunneling

Published Papers (4 papers)

by , , , ,  and
Molecules 2013, 18(11), 14349-14365; doi:10.3390/molecules181114349
Received: 9 September 2013; in revised form: 20 October 2013 / Accepted: 28 October 2013 / Published: 20 November 2013
Show/Hide Abstract | PDF Full-text (648 KB) | Supplementary Files

by ,  and
Molecules 2013, 18(12), 14470-14495; doi:10.3390/molecules181214470
Received: 22 September 2013; in revised form: 15 November 2013 / Accepted: 19 November 2013 / Published: 25 November 2013
Show/Hide Abstract | Cited by 1 | PDF Full-text (983 KB)

by , , ,  and
Molecules 2014, 19(1), 233-246; doi:10.3390/molecules19010233
Received: 8 October 2013; in revised form: 12 December 2013 / Accepted: 13 December 2013 / Published: 24 December 2013
Show/Hide Abstract | PDF Full-text (731 KB) | HTML Full-text | XML Full-text

by ,  and
Molecules 2014, 19(2), 2299-2329; doi:10.3390/molecules19022299
Received: 25 October 2013; in revised form: 7 January 2014 / Accepted: 28 January 2014 / Published: 21 February 2014
Show/Hide Abstract | PDF Full-text (1717 KB) | HTML Full-text | XML Full-text
abstract graphic

Last update: 3 April 2013

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