Synthesis and Evaluation of Novel Anticancer Agents
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Chemical Biology".
Deadline for manuscript submissions: closed (1 July 2023) | Viewed by 8408
Special Issue Editors
Interests: Structural elucidation; marine secondary metabolites; marine natural products; biological activities; cytotoxic mechanism; in vitro and in vivo assays
Special Issues, Collections and Topics in MDPI journals
Interests: apoptosis; cell culture; cancer biology; flow cytometry
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
One of the most influential synthetic chemists, Nobel Laurate Prof. Robert Burns Woodward, once said “The synthesis of substances occurring in Nature, perhaps in greater measure than activities in any other area of organic chemistry, provides a measure of the conditions and powers of science.” Since the advent of industrial and scientific revolution in the mid of nineteenth century, scientists always tried to mimic natural products and extensively researched on the most efficient methodologies for their synthesis. Many breakthroughs were reported in the synthesis of natural products since the production of the first natural compound, ammonia. To date, more than 60% of synthetic drugs are derived from natural sources and many analogs were developed based on natural scaffolds including Taxoteres, Jevtanas, Camptobells, Hycamtins, Camptosars, Velbans, Oncovins, Eldisines and Navelbines. In the current special issue, we would like to highlight the most important recent findings in the field of synthesis of anticancer agents and the evaluation of their biological activities. Contributors are encouraged to submit manuscripts and reviews covering but not limited to the following topics:
- Synthesis of novel anticancer agents and evaluation of their biological activity.
- Application of new technologies in the synthesis of known anticancer agents.
- Application of green technologies for the preparation of novel and known anticancer agents.
- Application of computational methods for the design of novel anticancer agents.
- Synthesis of novel anticancer analogs and study their synergistic or antagonistic affects with other anticancer agents.
- Development of new models for the evaluation of anticancer agents including 3D cell techniques and ex vivo models.
- Development of computational methods for the biological evaluation of anticancer agents.
- Application of biotechnological methods for the synthesis of anticancer agents.
Prof. Dr. Mei-Chin Lu
Prof. Dr. Mohamed El-Shazly
Guest Editors
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Keywords
- Anticancer agents
- Synthesis of natural product
- Organic methodologies
- computational methods
- Design, synthesis and evaluation
- biological activity
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