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Special Issue "In Vitro and In Vivo Approaches in the Driving Seat of Marine Drugs Discovery"

A special issue of Marine Drugs (ISSN 1660-3397).

Deadline for manuscript submissions: 30 November 2018

Special Issue Editor

Guest Editor
Prof. Mei-Chin Lu

Graduate Institute of Marine Biology, National Dong Hwa University, Taiwan
Website | E-Mail
Interests: structural elucidation; marine secondary metabolites; marine natural products; biological activities; cytotoxic mechanism; in vitro and in vivo assays

Special Issue Information

Dear Colleagues,

Isaac Newton once said, “I don't know what I may seem to the world, but as to myself, I seem to have been only like a boy playing on the sea-shore and diverting myself in now and then finding a smoother pebble or a prettier shell than ordinary, whilst the great ocean of truth lay all undiscovered before me.” Despite three centuries of great scientific discoveries, the truth about oceans and their organisms remains elusive. Natural products, medicinal and synthetic chemists along with pharmacologists, biochemists, cell biologists and microbiologists united their forces to unleash hidden treasures of oceans and seas. New classes of secondary metabolites were discovered from marine organisms with an unprecedented spectrum of biological activities. Several compounds entered the drug pipeline and many others are in various stages of clinical trials. Scientists used all available biological assays to screen marine organism extracts and fractions to zoom in on the most important compounds.

This Special Issue of Marine Drugs entitled “In Vitro and In Vivo Approaches in the Driving Seat of Marine Drugs Discovery” focuses on presenting the most recent advances in biological assays applied for the discovery of marine secondary metabolites with potential biological activities. Full research papers, short notes and review articles reporting the applications of in vitro and in vivo assays to reveal biological activities of marine natural products, will be considered. Colleagues are invited to present their research on biochemical and cell line assays along with pharmacokinetics, pharmacodynamics and disease models. They are also encouraged to present the most recent discoveries in new targets and assays for accelerating the process of drug discovery.

Prof. Mei-Chin Lu
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Marine Drugs is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • Marine secondary metabolites
  • Biological activities
  • In vitro assays
  • In vivo assays
  • Drug discovery

Published Papers

This special issue is now open for submission.

Journal Contact

Marine Drugs Editorial Office
St. Alban-Anlage 66, 4052 Basel, Switzerland
Tel. +41 61 683 77 34
Fax: +41 61 302 89 18
Editorial Board
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