Special Issue "Marine Compounds and Inflammation"
A special issue of Marine Drugs (ISSN 1660-3397).
Deadline for manuscript submissions: closed (30 April 2013)
Prof. Dr. Agostino Casapullo
Department of Pharmaceutical and Biomedical Sciences, University of Salerno, via Ponte don Melillo, 84084 Fisciano, Italy
Phone: +39 089 969243
Fax: +39 089 969602
Interests: marine natural products; structure elucidation; chemical proteomics; target discovery; bioorganic chemistry
Oceans cover about 70% of the earth’s surface and marine organisms comprise approximately a half of the total biodiversity. Marine natural products possess a unique chemical diversity and have evolved for optimal interactions with biological macromolecules, constituting an enormous library of novel compounds with wide biological properties useful in the drug discovery process.
The search for new drugs is currently moving toward a rationalization in which chemistry and pharmacology are joined into a targeted approach to drug discovery, focused on specific diseases and molecular targets. In this context, inflammation is increasingly considered a crucial biological pathway, due to its involvement in a large number of diseases such as allergies, asthma, rheumatoid arthritis, inflammatory bowel diseases, atherosclerosis, and in particular in the initiation and progression cancer, strictly implicated in many inflammatory processes such as increased angiogenesis and DNA synthesis, genomic damage, cellular proliferation, disruption of DNA repair pathways, and inhibition of apoptosis. On this basis, the exploration of marine sources in search of novel chemical scaffolds for the treatment of inflammatory-driven diseases represents a key pharmacological goal.
As the Guest Editor, I would like to invite scientists to report their findings in the field of marine anti-inflammatory compounds.
Prof. Dr. Agostino Casapullo
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Marine Drugs is an international peer-reviewed Open Access monthly journal published by MDPI.
- marine natural products
- transcription factors
- drug discovery
- anti-inflammatory effects
- bioactive compounds
- marine pharmaceuticals
- autoimmune diseases
- intracellular signaling pathways
Article: Soft Coral-Derived Lemnalol Alleviates Monosodium Urate-Induced Gouty Arthritis in Rats by Inhibiting Leukocyte Infiltration and iNOS, COX-2 and c-Fos Protein Expression
Mar. Drugs 2013, 11(1), 99-113; doi:10.3390/md11010099
Received: 28 November 2012; in revised form: 21 December 2012 / Accepted: 26 December 2012 / Published: 10 January 2013| Cited by 3 | PDF Full-text (978 KB) | HTML Full-text | XML Full-text
Article: Differential in Gel Electrophoresis (DIGE) Comparative Proteomic Analysis of Macrophages Cell Cultures in Response to Perthamide C Treatment
Mar. Drugs 2013, 11(4), 1288-1299; doi:10.3390/md11041288
Received: 28 February 2013; in revised form: 19 March 2013 / Accepted: 1 April 2013 / Published: 17 April 2013| PDF Full-text (617 KB) | HTML Full-text | XML Full-text | Supplementary Files
Mar. Drugs 2013, 11(4), 1336-1350; doi:10.3390/md11041336
Received: 26 February 2013; in revised form: 22 March 2013 / Accepted: 27 March 2013 / Published: 22 April 2013| Cited by 1 | PDF Full-text (382 KB) | HTML Full-text | XML Full-text | Supplementary Files
Mar. Drugs 2013, 11(6), 1853-1865; doi:10.3390/md11061853
Received: 20 March 2013; in revised form: 19 April 2013 / Accepted: 10 May 2013 / Published: 29 May 2013| Cited by 1 | PDF Full-text (948 KB) | HTML Full-text | XML Full-text | Supplementary Files
Article: Perna canaliculus Lipid Complex PCSO-524™ Demonstrated Pain Relief for Osteoarthritis Patients Benchmarked against Fish Oil, a Randomized Trial, without Placebo Control
Mar. Drugs 2013, 11(6), 1920-1935; doi:10.3390/md11061920
Received: 20 March 2013; in revised form: 8 May 2013 / Accepted: 21 May 2013 / Published: 5 June 2013| PDF Full-text (400 KB) | HTML Full-text | XML Full-text
Mar. Drugs 2013, 11(7), 2314-2327; doi:10.3390/md11072314
Received: 24 April 2013; in revised form: 27 May 2013 / Accepted: 28 May 2013 / Published: 2 July 2013| Cited by 3 | PDF Full-text (2208 KB) | HTML Full-text | XML Full-text | Supplementary Files
Article: Lithothamnion muelleri Controls Inflammatory Responses, Target Organ Injury and Lethality Associated with Graft-versus-Host Disease in Mice
Mar. Drugs 2013, 11(7), 2595-2615; doi:10.3390/md11072595
Received: 3 May 2013; in revised form: 1 July 2013 / Accepted: 2 July 2013 / Published: 18 July 2013| Cited by 1 | PDF Full-text (954 KB) | HTML Full-text | XML Full-text | Supplementary Files
Mar. Drugs 2013, 11(8), 2741-2750; doi:10.3390/md11082741
Received: 17 June 2013; in revised form: 9 July 2013 / Accepted: 11 July 2013 / Published: 2 August 2013| Cited by 4 | PDF Full-text (506 KB) | HTML Full-text | XML Full-text | Supplementary Files
Mar. Drugs 2013, 11(8), 2917-2926; doi:10.3390/md11082917
Received: 20 June 2013; in revised form: 17 July 2013 / Accepted: 19 July 2013 / Published: 13 August 2013| PDF Full-text (503 KB) | HTML Full-text | XML Full-text | Supplementary Files
Article: Functional Metabolomics Uncovers Metabolic Alterations Associated to Severe Oxidative Stress in MCF7 Breast Cancer Cells Exposed to Ascididemin
Mar. Drugs 2013, 11(10), 3846-3860; doi:10.3390/md11103846
Received: 18 July 2013; in revised form: 26 August 2013 / Accepted: 29 August 2013 / Published: 11 October 2013| PDF Full-text (1112 KB) | HTML Full-text | XML Full-text
Review: Anti-Inflammatory Activities of Natural Products Isolated from Soft Corals of Taiwan between 2008 and 2012
Mar. Drugs 2013, 11(10), 4083-4126; doi:10.3390/md11104083
Received: 30 July 2013; in revised form: 12 September 2013 / Accepted: 13 September 2013 / Published: 23 October 2013| Cited by 2 | PDF Full-text (1175 KB) | HTML Full-text | XML Full-text
Article: Fucoidan Extracted from Fucus evanescens Prevents Endotoxin-Induced Damage in a Mouse Model of Endotoxemia
Mar. Drugs 2014, 12(2), 886-898; doi:10.3390/md12020886
Received: 7 November 2013; in revised form: 24 January 2014 / Accepted: 26 January 2014 / Published: 31 January 2014| Cited by 1 | PDF Full-text (1645 KB) | HTML Full-text | XML Full-text
Last update: 6 November 2012