Special Issue "Bioactive Compounds from Marine Microbes"
A special issue of Marine Drugs (ISSN 1660-3397).
Deadline for manuscript submissions: closed (30 November 2014)
Dr. Kirk R. Gustafson
Molecular Targets Laboratory, Center for Cancer Research, National Cancer Institute, Building 562, Room 201, Frederick, MD 21702-1201, USA
Fax: +1 301 846 6157
Interests: natural products chemistry; chemical biology of natural products; NMR spectroscopy
The marine environment is a vast and largely unexplored resource for accessing diverse communities of microorganisms with novel biosynthetic capabilities. Marine habitats provide unique conditions for microbial growth and secondary metabolite expression that are not found in terrestrial ecosystems. The co-evolution of many marine macroorganisms, particularly invertebrate animals, with these microbes has often lead to the development of very close associations or symbiotic relationships between the host organism and a specific microbe. This in turn has resulted in the development and elaboration of unique microbial biosynthetic pathways and capabilities that can be utilized to generate novel compounds. Marine sediments are also now recognized as a rich source of microbial taxonomic diversity and new biologically active compounds. Efforts to cultivate and evaluate marine microorganisms and the associated compounds they can produce have expanded significantly in recent years, but this are of study is still very much in its infancy considering the vastness of the marine environment and the different types of microbial habitats found there.
Kirk R. Gustafson Ph. D.
- metabolic modulators and elicitors
- micro algae
- quorum sensing