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Oleic Acid Produced by a Marine Vibrio spp. Acts as an Anti-Vibrio parahaemolyticus Agent
Microbial Ecology Laboratory, Faculty of Marine Resources, Antofagasta University, Antofagasta 1310000, Chile
Doctorate Applied Science, Mention Coastal Marine Systems, Faculty of Marine Resources, Antofagasta University, Antofagasta 1310000, Chile
Laboratory of Natural Products, Department of Chemistry, Antofagasta University, Antofagasta 1310000, Chile
Institute of Natural Products and Agrobiology, CSIC, La Laguna, Tenerife 38206, Spain
* Author to whom correspondence should be addressed.
Received: 19 July 2011; in revised form: 13 August 2011 / Accepted: 23 August 2011 / Published: 24 October 2011
Abstract: It is known that some strains of Vibrio parahaemolyticus are responsible for gastroenteric diseases caused by the ingestion of marine organisms contaminated with these bacterial strains. Organic products that show inhibitory activity on the growth of the pathogenic V. parahaemolyticus were extracted from a Vibrio native in the north of Chile. The inhibitory organic products were isolated by reverse phase chromatography and permeation by Sephadex LH20, and were characterized by spectroscopic and spectrometric techniques. The results showed that the prevailing active product is oleic acid, which was compared with standards by gas chromatography and high-performance liquid chromatography (HPLC). These active products might be useful for controlling the proliferation of pathogenic clones of V. parahaemolyticus.
Keywords: bioactive marine products; inhibition; Vibrio parahaemolyticus; oleic acid
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Leyton, Y.; Borquez, J.; Darias, J.; Cueto, M.; Díaz-Marrero, A.R.; Riquelme, C. Oleic Acid Produced by a Marine Vibrio spp. Acts as an Anti-Vibrio parahaemolyticus Agent. Mar. Drugs 2011, 9, 2155-2163.
Leyton Y, Borquez J, Darias J, Cueto M, Díaz-Marrero AR, Riquelme C. Oleic Acid Produced by a Marine Vibrio spp. Acts as an Anti-Vibrio parahaemolyticus Agent. Marine Drugs. 2011; 9(10):2155-2163.
Leyton, Yanett; Borquez, Jorge; Darias, José; Cueto, Mercedes; Díaz-Marrero, Ana R.; Riquelme, Carlos. 2011. "Oleic Acid Produced by a Marine Vibrio spp. Acts as an Anti-Vibrio parahaemolyticus Agent." Mar. Drugs 9, no. 10: 2155-2163.