Special Issue "Plant-Derived Pharmaceuticals by Molecular Farming"
Deadline for manuscript submissions: closed (31 March 2011)
Prof. Dr. Chang Won Choi
Department of Biology & Medicinal Science, Pai Chai University, Daejeon 302-735, Korea
Phone: +8242 520 5617
Fax: +8242 520 5380
Interests: plant-derived biomedicines; plant-made pharmaceuticals; molecular farming; recombinant proteins; plant metabolic engineering; hypoglycaemic; hypolipidemic; antioxidants; antiviral
This special issue is aimed at both the basic and applied sciences of Plant Molecular Farming (PMF). PMF is the growing and harvesting of genetically engineered crops of transgenic plants, to produce biopharmaceuticals or industrial compounds instead of food, feed, or fibre. The possibilities cover from the manufacture of medical products, such as pharmaceuticals (drugs) and vaccines, to the products of industrial purpose like biodegradable plastics. The advantages of PMF in terms of production scale and economy, product safety, ease of storage and distribution are superior than any current commercial system. Despite the promising benefits, the commercialization of plant-derived pharmaceutical products is lagging by the uncertainty, particularly with regard to the adaptation of good manufacturing practice regulations to field-grown plants. Although it is not yet routinely commercialized, interest and investment in PMF are extending rapidly. PMF will be progressed for the core commercial development in biotechnology. Licensing of full scale production is forthcoming, although cultivated area in field will be very limited and highly regulated, or the initial stage of cultivation may begin in controlled greenhouses. The objective of this special issue is to provide high quality research results on novel gene expression in plants and its industrial or clinical application. I wish to thank all the authors for their contribution to this special issue.
Prof. Dr. Chang Won Choi
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed Open Access monthly journal published by MDPI.
- edible vaccines
- antibodies for diagnostic, preventative, and therapeutic applications
- bioplastics made from simple, biodegradable molecules produced in plants
- an enzyme used in the treatment of human and animals
- enzymes for use in food processing
- proteins for industrial purpose
Article: Membrane-Based Inverse Transition Cycling: An Improved Means for Purifying Plant-Derived Recombinant Protein-Elastin-Like Polypeptide Fusions
Int. J. Mol. Sci. 2011, 12(5), 2808-2821; doi:10.3390/ijms12052808
Received: 18 March 2011; in revised form: 11 April 2011 / Accepted: 11 April 2011 / Published: 29 April 2011| Download PDF Full-text (351 KB) | Download XML Full-text
Int. J. Mol. Sci. 2011, 12(5), 3220-3236; doi:10.3390/ijms12053220
Received: 1 April 2011; in revised form: 5 May 2011 / Accepted: 9 May 2011 / Published: 17 May 2011| Download PDF Full-text (204 KB) | Download XML Full-text
Int. J. Mol. Sci. 2011, 12(6), 3536-3552; doi:10.3390/ijms12063536
Received: 31 March 2011; in revised form: 11 May 2011 / Accepted: 27 May 2011 / Published: 3 June 2011| Download PDF Full-text (337 KB) | Download XML Full-text
Article: Interactions of Antibiotics and Methanolic Crude Extracts of Afzelia Africana (Smith.) Against Drug Resistance Bacterial Isolates
Int. J. Mol. Sci. 2011, 12(7), 4477-4487; doi:10.3390/ijms12074477
Received: 3 May 2011; in revised form: 9 June 2011 / Accepted: 4 July 2011 / Published: 13 July 2011| Download PDF Full-text (127 KB) | Download XML Full-text
Article: Transient Co-Expression of Post-Transcriptional Gene Silencing Suppressors for Increased in Planta Expression of a Recombinant Anthrax Receptor Fusion Protein
Int. J. Mol. Sci. 2011, 12(8), 4975-4990; doi:10.3390/ijms12084975
Received: 1 April 2011; in revised form: 18 June 2011 / Accepted: 20 July 2011 / Published: 5 August 2011| Download PDF Full-text (572 KB) | Download XML Full-text
Last update: 26 September 2012