Special Issue "Signal Transduction"
A special issue of Genes (ISSN 2073-4425).
Deadline for manuscript submissions: closed (31 January 2013)
Prof. Dr. Felix H. Brembeck (Website)
Tumor Biology and Signal Transduction, Department of Hematology and Oncology, University Medical Center Göttingen, Robert-Koch-Str. 40, 37075 Göttingen, Germany
Phone: +49 551 3912881
Fax: +49 551 3912534
Intracellular signaling is mediated by few highly conserved pathways which mediate elemental processes during embryonic development and in tissue homeostasis. Mutations of signal components within these transduction pathways are implicated in human disease such as cancer. Therefore the precise analysis of signal components and their interactions between different pathways has emerged as a challenging issue to understand tissue morphogenesis, regeneration and disease onset. Many functions have been elucidated from work in Drosophila, Xenopus and zebra fish and were re-evaluated for higher vertebrates during embryogenesis and in disease models.
This Special Issue of “Genes” welcomes reviews and original papers covering recent research on signal transduction to provide a link between different model organisms and their specific functions for signal transduction. Special interest will be given to reports on intracellular signaling using in vitro and in vivo models for development, stem cell control or disease.
Prof. Dr. Felix H. Brembeck
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Genes is an international peer-reviewed Open Access monthly journal published by MDPI.
- signal transduction
- tissue homeostasis
- embryonic stem cells
- cancer stem cells
- animal models