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Signaling Pathways from the Endoplasmic Reticulum and Their Roles in Disease
Genes 2013, 4(3), 334-357; doi:10.3390/genes4030334

Roles of EphA2 in Development and Disease

Susan Lehman-Cullman Laboratory for Cancer Research, Department of Chemical Biology, Ernest Mario School of Pharmacy, Rutgers University, Piscataway, NJ 08854, USA
* Author to whom correspondence should be addressed.
Received: 23 April 2013 / Revised: 22 May 2013 / Accepted: 23 May 2013 / Published: 1 July 2013
(This article belongs to the Special Issue Signal Transduction)
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The Eph family of receptor tyrosine kinases (RTKs) has been implicated in the regulation of many aspects of mammalian development. Recent analyses have revealed that the EphA2 receptor is a key modulator for a wide variety of cellular functions. This review focuses on the roles of EphA2 in both development and disease.
Keywords: EphA2; ephrin; development; cataract; kidney; bone; ear; mammary gland EphA2; ephrin; development; cataract; kidney; bone; ear; mammary gland
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Park, J.E.; Son, A.I.; Zhou, R. Roles of EphA2 in Development and Disease. Genes 2013, 4, 334-357.

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