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Genes 2013, 4(3), 334-357; doi:10.3390/genes4030334
Review

Roles of EphA2 in Development and Disease

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 and
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Susan Lehman-Cullman Laboratory for Cancer Research, Department of Chemical Biology, Ernest Mario School of Pharmacy, Rutgers University, Piscataway, NJ 08854, USA
* Author to whom correspondence should be addressed.
Received: 23 April 2013 / Revised: 22 May 2013 / Accepted: 23 May 2013 / Published: 1 July 2013
(This article belongs to the Special Issue Signal Transduction)
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Abstract

The Eph family of receptor tyrosine kinases (RTKs) has been implicated in the regulation of many aspects of mammalian development. Recent analyses have revealed that the EphA2 receptor is a key modulator for a wide variety of cellular functions. This review focuses on the roles of EphA2 in both development and disease.
Keywords: EphA2; ephrin; development; cataract; kidney; bone; ear; mammary gland EphA2; ephrin; development; cataract; kidney; bone; ear; mammary gland
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).
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Park, J.E.; Son, A.I.; Zhou, R. Roles of EphA2 in Development and Disease. Genes 2013, 4, 334-357.

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