Special Issue "Gene Silencing"
A special issue of Genes (ISSN 2073-4425).
Deadline for manuscript submissions: closed (15 May 2013)
Dr. Célia Baroux
Institute of Plant Biology, Basel-Zürich Plant Science Center, University of Zürich, Zollikerstr. 107, CH-8008 Zürich, Switzerland
Interests: epigenetics; cytogenetics; chromatin dynamics; plant development
The development of multicellular organisms and the operation of complex cellular function requires not only perfect orchestration of gene expression but also a precise spatial and temporal control of gene silencing. Gene silencing mechanisms are diverse and exquisitely refined. These mechanisms operate at the transcriptional and post-transcriptional levels, or during meiosis; they use a variety of cellular components such as cis-DNA elements, chromatin modifications, small and non-coding RNAs and specific protein factors responsible for the initiation, operation and readout of silencing.
Common scenarios of gene silencing are found in plants, insects, worms and mammals. Yet each organism reveal specific adaptations and regulations. Those are important to elucidate, not only for philosophical purposes (with the meaning of studying and understanding general and fundamental problems) but also for medical or biotechnological applications.
This Special issue of "Genes" welcomes reviews and original papers covering recent research in gene silencing at the mechanistic and regulation levels in different organisms, but also research bridging gene silencing and cellular function, development or biotechnological applications.
Dr. Célia Baroux
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Genes is an international peer-reviewed Open Access monthly journal published by MDPI.
- gene silencing
- genomic Imprinting
- transposon silencing
- transgene silencing
- position effect
- RNA-directed DNA methylation
- RNA interference
- nonsense mediated decay
- meiotic silencing of unpaired DNA