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32 Results Found

  • Article
  • Open Access
10 Citations
4,644 Views
20 Pages

12 August 2019

Metabolomics-based approaches are still receiving growing attention with regard to food authenticity testing. Such studies require enormous sample numbers with negligible experimental or analytical variations to obtain statistically reliable results....

(This article belongs to the Special Issue Mass Spectrometry-Based Metabolomics: Challenges and Applications)
  • Review
  • Open Access
34 Citations
7,358 Views
20 Pages

Human Milk Oligosaccharide Profiles and Associations with Maternal Nutritional Factors: A Scoping Review

  • Caren Biddulph,
  • Mark Holmes,
  • Anna Kuballa,
  • Peter S. W. Davies,
  • Pieter Koorts,
  • Roger J. Carter and
  • Judith Maher

17 March 2021

Human milk oligosaccharides (HMOs) are complex unconjugated glycans associated with positive infant health outcomes. This study has examined current knowledge of the effect of maternal diet and nutritional status on the composition of HMOs in breast...

(This article belongs to the Special Issue Advances in Breastfeeding and Human Milk Research)
  • Communication
  • Open Access
11 Citations
7,657 Views
9 Pages

Rapid Approach to Determine Propionic and Sorbic Acid Contents in Bread and Bakery Products Using 1H NMR Spectroscopy

  • Marwa Scharinger,
  • Marcel Kuntz,
  • Andreas Scharinger,
  • Jan Teipel,
  • Thomas Kuballa,
  • Stephan G. Walch and
  • Dirk W. Lachenmeier

3 March 2021

The food additive sorbic acid is considered as an effective preservative for certain cereal products, and propionic acid is commonly added in bakery wares, e.g., bread and fine bakery wares. The aim of this study was to develop and validate a new nuc...

(This article belongs to the Special Issue Quality and Composition Assessment of Wheat and Its Products)
  • Article
  • Open Access
64 Citations
13,138 Views
18 Pages

Coffee Silver Skin: Chemical Characterization with Special Consideration of Dietary Fiber and Heat-Induced Contaminants

  • Vera Gottstein,
  • Mara Bernhardt,
  • Elena Dilger,
  • Judith Keller,
  • Carmen M. Breitling-Utzmann,
  • Steffen Schwarz,
  • Thomas Kuballa,
  • Dirk W. Lachenmeier and
  • Mirko Bunzel

23 July 2021

Coffee silver skin is produced in large amounts as a by-product during the coffee roasting process. In this study, coffee silver skin of the species Coffea arabica L. and Coffea canephora Pierre ex A. Froehner as well as silver skin pellets produced...

(This article belongs to the Special Issue Latest Advances in Plant-Based Food Processing to Improve the Sustainability in the Food Supply Chain)
  • Review
  • Open Access
38 Citations
6,331 Views
18 Pages

4 August 2021

Deep learning is a trending field in bioinformatics; so far, mostly known for image processing and speech recognition, but it also shows promising possibilities for data processing in food analysis, especially, foodomics. Thus, more and more deep lea...

(This article belongs to the Special Issue Foodomics: New Approaches to Evaluate Food Quality)
  • Article
  • Open Access
8 Citations
3,906 Views
15 Pages

Microbial Diversity Profiling of Gut Microbiota of Macropus giganteus Using Three Hypervariable Regions of the Bacterial 16S rRNA

  • Christian O’Dea,
  • Roger Huerlimann,
  • Nicole Masters,
  • Anna Kuballa,
  • Cameron Veal,
  • Paul Fisher,
  • Helen Stratton and
  • Mohammad Katouli

Animal faecal contamination of surface waters poses a human health risk, as they may contain pathogenic bacteria or viruses. Of the numerous animal species residing along surface waterways in Australia, macropod species are a top contributor to wild...

(This article belongs to the Section Gut Microbiota)
  • Feature Paper
  • Article
  • Open Access
39 Citations
10,249 Views
20 Pages

A Quantitative 1H NMR Method for Screening Cannabinoids in CBD Oils

  • Ines Barthlott,
  • Andreas Scharinger,
  • Patricia Golombek,
  • Thomas Kuballa and
  • Dirk W. Lachenmeier

10 June 2021

Toxicologically relevant levels of the psychoactive ∆9-tetrahydocannabinol (∆9-THC) as well as high levels of non-psychoactive cannabinoids potentially occur in CBD (cannabidiol) oils. For consumer protection in the fast-growing CBD oil market, facil...

(This article belongs to the Topic Instrumental and Bioanalytical Methods for Food Contaminant Detection)
  • Article
  • Open Access
6 Citations
4,544 Views
11 Pages

12 March 2020

So far, only a few cases of immunoglobulin E (IgE)-mediated coconut allergies have been described in the literature. Due to a growing consumption of coconut-containing foods in occidental countries, the number of coconut allergies may also increase....

(This article belongs to the Section Food Analytical Methods)
  • Article
  • Open Access
5 Citations
3,972 Views
17 Pages

A Comparative Study of the Adherent-Invasive Escherichia coli Population and Gut Microbiota of Healthy Vegans versus Omnivores

  • Rebecca Veca,
  • Christian O’Dea,
  • Jarred Burke,
  • Eva Hatje,
  • Anna Kuballa and
  • Mohammad Katouli

Adherent-invasive Escherichia coli (AIEC) strains carry virulence genes (VGs) which are rarely found in strains other than E. coli. These strains are abundantly found in gut mucosa of patients with inflammatory bowel disease (IBD); however, it is not...

(This article belongs to the Section Gut Microbiota)
  • Article
  • Open Access
43 Citations
10,421 Views
11 Pages

Validation of a Quantitative Proton Nuclear Magnetic Resonance Spectroscopic Screening Method for Coffee Quality and Authenticity (NMR Coffee Screener)

  • Alex O. Okaru,
  • Andreas Scharinger,
  • Tabata Rajcic de Rezende,
  • Jan Teipel,
  • Thomas Kuballa,
  • Stephan G. Walch and
  • Dirk W. Lachenmeier

4 January 2020

Monitoring coffee quality as a means of detecting and preventing economically motivated fraud is an important aspect of international commerce today. Therefore, there is a compelling need for rapid high throughput validated analytical techniques such...

(This article belongs to the Special Issue Advances of Spectrometric Techniques in Food Analysis and Food Authentication Implemented with Chemometrics)
  • Article
  • Open Access
30 Citations
7,363 Views
19 Pages

Key Factors for a One-Pot Enzyme Cascade Synthesis of High Molecular Weight Hyaluronic Acid

  • Johannes Gottschalk,
  • Henning Zaun,
  • Anna Eisele,
  • Jürgen Kuballa and
  • Lothar Elling

12 November 2019

In the last decades, interest in medical or cosmetic applications of hyaluronic acid (HA) has increased. Size and dispersity are key characteristics of biological function. In contrast to extraction from animal tissue or bacterial fermentation, enzym...

(This article belongs to the Special Issue Molecular Biocatalysis 2.0)
  • Feature Paper
  • Article
  • Open Access
1 Citations
4,161 Views
25 Pages

NMPC-Based Workflow for Simultaneous Process and Model Development Applied to a Fed-Batch Process for Recombinant C. glutamicum

  • Philipp Levermann,
  • Fabian Freiberger,
  • Uma Katha,
  • Henning Zaun,
  • Johannes Möller,
  • Volker C. Hass,
  • Karl Michael Schoop,
  • Jürgen Kuballa and
  • Ralf Pörtner

19 October 2020

For the fast and improved development of bioprocesses, new strategies are required where both strain and process development are performed in parallel. Here, a workflow based on a Nonlinear Model Predictive Control (NMPC) algorithm is described for t...

(This article belongs to the Section Biological Processes and Systems)
  • Article
  • Open Access
10 Citations
4,646 Views
17 Pages

Endotoxin Tolerance in Abdominal Aortic Aneurysm Macrophages, In Vitro: A Case–Control Study

  • Lara T. Meital,
  • Mark T. Windsor,
  • Alesiya E. Maynard,
  • Karl Schulze,
  • Rebecca Magee,
  • Jill O’Donnell,
  • Pankaj Jha,
  • Chaim Y. Meital,
  • Maria Perissiou and
  • Fraser D. Russell
  • + 5 authors

21 September 2020

Macrophages are implicated in the pathogenesis of abdominal aortic aneurysm (AAA). This study examined the environmentally conditioned responses of AAA macrophages to inflammatory stimuli. Plasma- and blood-derived monocytes were separated from the w...

(This article belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
  • Article
  • Open Access
26 Citations
6,604 Views
20 Pages

Application of 1H Nuclear Magnetic Resonance Spectroscopy as Spirit Drinks Screener for Quality and Authenticity Control

  • Jan C. Teipel,
  • Thomas Hausler,
  • Katharina Sommerfeld,
  • Andreas Scharinger,
  • Stephan G. Walch,
  • Dirk W. Lachenmeier and
  • Thomas Kuballa

24 September 2020

Due to legal regulations, the rise of globalised (online) commerce and the need for public health protection, the analysis of spirit drinks (alcoholic beverages >15% vol) is a task with growing importance for governmental and commercial laboratori...

(This article belongs to the Section Food Engineering and Technology)
  • Article
  • Open Access
16 Citations
4,562 Views
14 Pages

Associations between Maternal Nutrition and the Concentrations of Human Milk Oligosaccharides in a Cohort of Healthy Australian Lactating Women

  • Caren Biddulph,
  • Mark Holmes,
  • Trong D. Tran,
  • Anna Kuballa,
  • Peter S. W. Davies,
  • Pieter Koorts and
  • Judith Maher

26 April 2023

Human milk oligosaccharides (HMOs) are complex glycans associated with positive infant health outcomes. The concentrations of HMOs in the milk of lactating women are associated with substantial intra- and inter-individual differences and may be influ...

(This article belongs to the Special Issue Sustainable Nutrition—Healthy People)
  • Feature Paper
  • Article
  • Open Access
18 Citations
10,359 Views
10 Pages

An Easy and Reliable Method for the Mitigation of Deuterated Chloroform Decomposition to Stabilise Susceptible NMR Samples

  • Jan Teipel,
  • Vera Gottstein,
  • Eva Hölzle,
  • Katja Kaltenbach,
  • Dirk W. Lachenmeier and
  • Thomas Kuballa

2 August 2022

Highly reactive decomposition products of deuterated chloroform can deteriorate samples dissolved in this commonly used solvent for nuclear magnetic resonance (NMR) spectroscopy. Samples for metabolomics studies often contain a complex mixture of sen...

(This article belongs to the Topic Recent Trends and Advances in Food Authentication and Traceability)
  • Article
  • Open Access
51 Citations
23,439 Views
12 Pages

Ethyl carbamate (EC) is a recognized genotoxic carcinogen, with widespread occurrence in fermented foods and beverages. No data on its occurrence in alcoholic beverages from Mexico or Central America is available. Samples of agave spirits including t...

(This article belongs to the Special Issue Environmental Research on Alcohol: Public Health Perspectives)
  • Article
  • Open Access
54 Citations
10,676 Views
13 Pages

Potential Antagonistic Effects of Acrylamide Mitigation during Coffee Roasting on Furfuryl Alcohol, Furan and 5-Hydroxymethylfurfural

  • Dirk W. Lachenmeier,
  • Steffen Schwarz,
  • Jan Teipel,
  • Maren Hegmanns,
  • Thomas Kuballa,
  • Stephan G. Walch and
  • Carmen M. Breitling-Utzmann

21 December 2018

The four heat-induced coffee contaminants—acrylamide, furfuryl alcohol (FA), furan and 5-hydroxymethylfurfural (HMF)—were analyzed in a collective of commercial samples as well as in Coffea arabica seeds roasted under controlled condition...

(This article belongs to the Special Issue Analysis of Chemical Contaminants in Food)
  • Article
  • Open Access
4 Citations
3,000 Views
15 Pages

Effects of an Integrative Day Care Clinic Program with a Focus on Nature Therapy in a Hospital Park Setting on Quality of Life in Oncological Patients—A Non-Randomized Controlled Study

  • Lisa Kuballa,
  • Christian S. Kessler,
  • Farid I. Kandil,
  • Christel von Scheidt,
  • Meline Meinköhn,
  • Barbara Koch,
  • Manfred Wischnewsky,
  • Andreas Michalsen and
  • Michael Jeitler

16 September 2023

Cancer often causes long-term physical and psychological impairments. Lifestyle modification and nature-based interventions (NBIs) can have a positive impact on patients’ quality of life (QOL). This participants-blinded, non-randomized controll...

(This article belongs to the Collection Oncology: State-of-the-Art Research in Germany)
  • Article
  • Open Access
19 Citations
2,978 Views
14 Pages

Comparative Analysis of LC-ESI-IM-qToF-MS and FT-NIR Spectroscopy Approaches for the Authentication of Organic and Conventional Eggs

  • Henri Lösel,
  • Johannes Brockelt,
  • Florian Gärber,
  • Jan Teipel,
  • Thomas Kuballa,
  • Stephan Seifert and
  • Markus Fischer

The importance of animal welfare and the organic production of chicken eggs has increased in the European Union in recent years. Legal regulation for organic husbandry makes the production of organic chicken eggs more expensive compared to convention...

(This article belongs to the Section Nutrition and Metabolism)
  • Article
  • Open Access
7 Citations
8,197 Views
15 Pages

Monitoring of Chemical Changes in Coffee Beans during the Roasting Process Using Different Roasting Technologies with Nuclear Magnetic Resonance Spectroscopy

  • Vera Gottstein,
  • Katrin Krumbügel,
  • Thomas Kuballa,
  • Steffen Schwarz,
  • Enrico Walch,
  • Pascal Walch and
  • Dirk W. Lachenmeier

12 October 2023

The roasting process is an important step in coffee production, leading to important physical and chemical changes that are responsible for the sensory quality of a coffee beverage. Besides the commonly used drum roasters, a newly developed infrared...

(This article belongs to the Section Tea, Coffee, Water, and Other Non-Alcoholic Beverages)
  • Review
  • Open Access
8 Citations
4,165 Views
15 Pages

25 May 2022

The assessment of body composition during lactation is an important indicator of maternal nutritional status, which is central to the overall health of the mother and child. The lactating woman’s nutritional status potentially impacts on breast...

(This article belongs to the Section Nutrition in Women)
  • Article
  • Open Access
8 Citations
4,183 Views
13 Pages

Efficacy of Selected Live Biotherapeutic Candidates to Inhibit the Interaction of an Adhesive-Invasive Escherichia coli Strain with Caco-2, HT29-MTX Cells and Their Co-Culture

  • Bronwyn Smit,
  • Chiemeka C. Chinaka,
  • Albert A. Scott,
  • Kirsten Gaiduschek,
  • Eva Hatje,
  • Anna Kuballa,
  • Samantha Coulson,
  • Wayne Finlayson and
  • Mohammad Katouli

Adherent-invasive Escherichia coli (AIEC) has been implicated as a microbiological factor in the pathogenesis of inflammatory bowel disease (IBD). We evaluated the ability of six live biotherapeutic products (LBPs) to inhibit the interaction of an AI...

(This article belongs to the Special Issue Molecular and Translational Research of the Microbiome in Infectious and Non-infectious Diseases)
  • Article
  • Open Access
5 Citations
3,152 Views
14 Pages

Identification of Virulence Genes Associated with Pathogenicity of Translocating Escherichia coli with Special Reference to the Type 6 Secretion System

  • Behnoush Asgari,
  • Jarred R. Burke,
  • Bonnie L. Quigley,
  • Georgia Bradford,
  • Eva Hatje,
  • Anna Kuballa and
  • Mohammad Katouli

Recent genomic characterisation of translocating Escherichia coli HMLN-1 isolated from mesenteric lymph nodes (MLNs) and blood of a patient with a fatal case of pancreatitis revealed the presence of a type 6 secretion system (T6SS) that was not prese...

(This article belongs to the Section Gut Microbiota)
  • Article
  • Open Access
1 Citations
3,553 Views
13 Pages

Resilient Enzymes through Immobilisation: Stable NDP Polyphosphate Phosphotransferase from Ruegeria pomeroyi for Nucleotide Regeneration

  • Kristin Hölting,
  • Sebastian Götz,
  • Miriam Aßmann,
  • Paul Bubenheim,
  • Andreas Liese and
  • Jürgen Kuballa

24 February 2024

Immobilisation plays an important role in the industrial application of enzymes. The stabilisation and reusability of immobilised enzymes reduce the cost of the catalyst and facilitate their use in continuously operated reactors. For this purpose, an...

(This article belongs to the Special Issue Supported Biocatalysts for Sustainable Chemistry)
  • Article
  • Open Access
14 Citations
7,741 Views
13 Pages

The gastrointestinal tract’s microbiota plays a crucial role in human health, with dysbiosis linked to the development of diseases such as inflammatory bowel disease (IBD). Whilst the pathogenic mechanisms underlying IBD remain poorly character...

(This article belongs to the Special Issue Probiotics, Prebiotics, and Gut Microbes)
  • Article
  • Open Access
6 Citations
3,035 Views
20 Pages

The Shelf Life of Milk—A Novel Concept for the Identification of Marker Peptides Using Multivariate Analysis

  • Lisa-Carina Class,
  • Gesine Kuhnen,
  • Kim Lara Hanisch,
  • Svenja Badekow,
  • Sascha Rohn and
  • Jürgen Kuballa

8 March 2024

The quality of food is influenced by several factors during production and storage. When using marker compounds, different steps in the production chain, as well as during storage, can be monitored. This might enable an optimum prediction of food&rsq...

(This article belongs to the Section Dairy)
  • Review
  • Open Access
10 Citations
13,263 Views
20 Pages

16 November 2023

As early as 1946, Felix Bloch and Edward Mills Purcell detected nuclear magnetic resonance signals, earning themselves the Nobel Prize in 1952. The same year saw the launch of the first commercial nuclear magnetic resonance (NMR) spectrometer. Since...

  • Article
  • Open Access
1 Citations
4,028 Views
16 Pages

NMR Analysis of Pulegone in Food Products

  • Yifei Yu,
  • Thomas Kuballa and
  • Dirk W. Lachenmeier

22 November 2024

Pulegone is a monoterpene ketone found in a variety of mint species. It has been classified as possibly carcinogenic to humans (Group 2B) by the International Agency for Research on Cancer (IARC). In previous studies, pulegone in food was analyzed ex...

(This article belongs to the Special Issue Recent Applications of Plant Extracts in the Food Industry)
  • Article
  • Open Access
1 Citations
2,239 Views
20 Pages

18 October 2024

The diminishing of food waste is gaining increasing importance, especially in context with a growing population and a need for the sustainable use of food resources. A more precise determination of the best-before date can contribute to this general...

(This article belongs to the Section Food Quality and Safety)
  • Feature Paper
  • Article
  • Open Access
1 Citations
2,878 Views
25 Pages

Modelling Approach for the Continuous Biocatalytic Synthesis of N-Acetylneuraminic Acid in Packed Bed Reactors

  • Kristin Hölting,
  • Miriam Aßmann,
  • Paul Bubenheim,
  • Andreas Liese and
  • Jürgen Kuballa

9 October 2024

Continuous flow technologies have become increasingly important for biocatalytic processes. In this study, we present the application and modelling of covalently immobilised N-acetylglucosamine 2-epimerase and N-acetylneuraminic acid lyase in packed...

(This article belongs to the Special Issue Development, Modelling and Simulation of Biocatalytic Processes)
  • Article
  • Open Access
1,451 Views
16 Pages

Probiotics have been widely adopted due to their beneficial health properties. Here, we investigated the interactions of a probiotic Limosilactobacillus (Lactobacillus) reuteri M4-100, with a translocating Escherichia coli strain HMLN-1, in a co-cult...

(This article belongs to the Section Medical Microbiology)