Special Issue "Toxin-Antibody Interactions"

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A special issue of Toxins (ISSN 2072-6651).

Deadline for manuscript submissions: closed (31 January 2014)

Special Issue Editor

Guest Editor
Dr. Nicholas J. Mantis
Division of Infectious Disease, Wadsworth Center, New York State Department of Health, 120 New Scotland Avenue, Albany, NY 12208, USA
Website: http://www.wadsworth.org/resnres/bios/mantis_pubs.html
E-Mail: nmantis@wadsworth.org
Phone: +1 518 473 7487
Fax: +1 518 402 4773
Interests: plant and bacterial protein toxins; neutralizing antibodies; vaccines; mucosal tissues; animal models; small molecule inhibitors

Special Issue Information

Dear Colleagues,

Antibodies are remarkable in their ability to inactivate even the most potent plant and microbial toxins, including botulinum, tetanus, diphtheria, anthrax and ricin toxins.  While this fact has been recognized for more than a century, surprisingly little is known about the molecular mechanisms by which antibodies actually neutralize toxins.  Indeed, historically, there has been little incentive to investigate the nature of toxin-antibody interactions because of the success of so many toxin vaccines and therapies.  However, this has changed in the past decade with the global demand in the public health and biodefense sectors for new generation antibody-based countermeasures that are safer and more effective.   With the surge in new research, it is now becoming increasingly apparent that the interactions between toxins-antibodies are as complex, sophisticated and interesting as the toxins themselves.

The goal of this special issue of Toxins is to provide a state-of-the-art look into the diverse mechanisms by which antibodies neutralize toxins and insights into how understanding these interactions will have applications for next generation vaccines and therapeutics.

Dr. Nicholas J. Mantis
Guest Editor

Submission

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Toxins is an international peer-reviewed Open Access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1000 CHF (Swiss Francs).

Keywords

  • antibody
  • neutralization
  • protection
  • clearance
  • vaccine
  • therapeutics

Published Papers (12 papers)

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Displaying article 1-12
p. 1799-1812
by  and
Toxins 2014, 6(6), 1799-1812; doi:10.3390/toxins6061799
Received: 7 March 2014; in revised form: 23 April 2014 / Accepted: 15 May 2014 / Published: 10 June 2014
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(This article belongs to the Special Issue Toxin-Antibody Interactions)
p. 1512-1525
by , , , ,  and
Toxins 2014, 6(5), 1512-1525; doi:10.3390/toxins6051512
Received: 4 February 2014; in revised form: 24 March 2014 / Accepted: 28 March 2014 / Published: 7 May 2014
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(This article belongs to the Special Issue Toxin-Antibody Interactions)
p. 1385-1396
by , , , , , , , ,  and
Toxins 2014, 6(4), 1385-1396; doi:10.3390/toxins6041385
Received: 6 February 2014; in revised form: 6 March 2014 / Accepted: 9 April 2014 / Published: 22 April 2014
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(This article belongs to the Special Issue Toxin-Antibody Interactions)
p. 1325-1348
by , , ,  and
Toxins 2014, 6(4), 1325-1348; doi:10.3390/toxins6041325
Received: 10 February 2014; in revised form: 10 March 2014 / Accepted: 28 March 2014 / Published: 11 April 2014
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(This article belongs to the Special Issue Toxin-Antibody Interactions)
p. 380-393
by , , ,  and
Toxins 2014, 6(1), 380-393; doi:10.3390/toxins6010380
Received: 10 December 2013; in revised form: 10 January 2014 / Accepted: 10 January 2014 / Published: 21 January 2014
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(This article belongs to the Special Issue Toxin-Antibody Interactions)
p. 2589-2620
by
Toxins 2013, 5(12), 2589-2620; doi:10.3390/toxins5122589
Received: 31 October 2013; in revised form: 9 December 2013 / Accepted: 13 December 2013 / Published: 18 December 2013
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(This article belongs to the Special Issue Toxin-Antibody Interactions)
p. 568-589
by , , , , , , , ,  and
Toxins 2013, 5(3), 568-589; doi:10.3390/toxins5030568
Received: 9 January 2013; in revised form: 28 February 2013 / Accepted: 5 March 2013 / Published: 19 March 2013
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(This article belongs to the Special Issue Toxin-Antibody Interactions)
p. 1565-1581
by , , , , , ,  and
Toxins 2012, 4(12), 1565-1581; doi:10.3390/toxins4121565
Received: 22 November 2012; in revised form: 13 December 2012 / Accepted: 13 December 2012 / Published: 19 December 2012
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(This article belongs to the Special Issue Toxin-Antibody Interactions)
p. 1451-1467
by , , , , , , ,  and
Toxins 2012, 4(12), 1451-1467; doi:10.3390/toxins4121451
Received: 22 August 2012; in revised form: 16 November 2012 / Accepted: 28 November 2012 / Published: 5 December 2012
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(This article belongs to the Special Issue Toxin-Antibody Interactions)
p. 729-747
by , , , , , ,  and
Toxins 2012, 4(9), 729-747; doi:10.3390/toxins4090729
Received: 28 August 2012; in revised form: 17 September 2012 / Accepted: 17 September 2012 / Published: 18 September 2012
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(This article belongs to the Special Issue Toxin-Antibody Interactions)
p. 554-567
by , , , ,  and
Toxins 2012, 4(7), 554-567; doi:10.3390/toxins4070554
Received: 19 June 2012; in revised form: 26 June 2012 / Accepted: 6 July 2012 / Published: 19 July 2012
Show/Hide Abstract | Cited by 6 | PDF Full-text (1125 KB) | HTML Full-text | XML Full-text | Supplementary Files
(This article belongs to the Special Issue Toxin-Antibody Interactions)
p. 430-454
by  and
Toxins 2012, 4(6), 430-454; doi:10.3390/toxins4060430
Received: 29 April 2012; in revised form: 6 June 2012 / Accepted: 7 June 2012 / Published: 11 June 2012
Show/Hide Abstract | Cited by 4 | PDF Full-text (526 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Toxin-Antibody Interactions)
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Last update: 4 March 2014

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