Special Issue "Cantilever, Microcantilevers and Nanocantilever Sensors and Biosensors"

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A special issue of Sensors (ISSN 1424-8220). This special issue belongs to the section "Biosensors".

Deadline for manuscript submissions: closed (30 April 2008)

Special Issue Editor

Guest Editor
Dr. Montserrat Calleja
Instituto de Microelectrónica de Madrid Isaac Newton, 8, Tres Cantos, E-28760
Website: http://www.imm-cnm.csic.es/bionano/en
E-Mail: mcalleja@imm.cnm.csic.es

Special Issue Information

Dear Colleagues,

In the last years, microcantilevers have been increasingly used as mechanical transducers of molecular recognition and for the development of miniaturized and sensitive biochip platforms. The principle is that intermolecular forces that result from molecular recognition events on the sensitised surface of a cantilever produce its nano-scale motion. Main techniques for the nanomechanical response include the optical lever method, interferometry-based methods, and the piezoresistivity technique. The optical lever method is the most extended due to the extreme accuracy and easy implementation for measuring cantilevers immersed in liquids. The applications include detection of cancer protein markers, pesticides, DNA hybridisation and pathogens. The great interest in these recent kind of biosensors relies on the label-free detection, high sensitivity, small sensor area, and the potential for simultaneous detection of tens, or even hundreds, of targets by making use of arrays of cantilevers. In fact, cantilever arrays can be mass-fabricated at low cost by adopting well-known semiconductor technology. Also, with microelectronics technology now pushing deep into the submicron regime, nanoelectromechanical systems (NEMS) are drawing interest from the scientific community for a wide range of applications due to their unique properties. Nanocantilevers are among those of the possible NEMS realizations that offer access to a parameter space that is unprecedented; fundamental resonant frequencies in the microwaves, active masses in the femtograms, heat capacities below a yoctocalorie, to name a few. Nanocantilever resonators have been proposed for ultrafast sensors and actuators, signal processing components and for quantum computing. Recent experiments have open up a new application, mass detection based on nanoresonators. The minuscule active mass of this elements allow to envision the detection of single molecules.

Topics

  • Detection of gases and chemicals
  • Biological detection
  • Theoretical understanding of the nanomechanical response
  • Fabrication of cantilever arrays for nanomechanical sensors
  • Nanocantilevers
  • Integration of nanomechanical sensors (microfluidics, actuators, sensors, CMOS)
  • MEMS/NEMS technology for sensors
  • SPM technology for molecular recognition imaging
  • Transduction methods of the nanomechanical signal

Dr. Montserrat Calleja
Guest Editor

Keywords

  • microcantilever-based biosensors
  • surface stress measurements
  • mass detection
  • microcantilevers
  • nanocantilevers
  • nano-micromechanical resonators
  • nanomechanical sensors
  • nanomechanics
  • NEMS
  • MEMS
  • nanoresonators

Published Papers (12 papers)

by ,  and
Sensors 2008, 8(7), 4466-4486; doi:10.3390/s8074466
Received: 4 March 2008; in revised form: 16 May 2008 / Accepted: 16 May 2008 / Published: 29 July 2008
Show/Hide Abstract | Cited by 10 | PDF Full-text (879 KB) | HTML Full-text | XML Full-text

by ,  and
Sensors 2008, 8(5), 3497-3541; doi:10.3390/s8053497
Received: 17 April 2008; Accepted: 18 May 2008 / Published: 26 May 2008
Show/Hide Abstract | Cited by 27 | PDF Full-text (473 KB) | HTML Full-text | XML Full-text

by , , , , , , ,  and
Sensors 2008, 8(3), 1595-1612; doi:10.3390/s8031595
Received: 2 November 2007; Accepted: 3 March 2008 / Published: 10 March 2008
Show/Hide Abstract | Cited by 37 | PDF Full-text (659 KB) | HTML Full-text | XML Full-text

by ,  and
Sensors 2008, 8(1), 10-22; doi:10.3390/s8010010
Received: 29 October 2007; Accepted: 4 January 2008 / Published: 9 January 2008
Show/Hide Abstract | Cited by 10 | PDF Full-text (3557 KB) | HTML Full-text | XML Full-text

by  and
Sensors 2008, 8(1), 23-34; doi:10.3390/s8010023
Received: 31 October 2007; Accepted: 2 January 2008 / Published: 9 January 2008
Show/Hide Abstract | Cited by 3 | PDF Full-text (239 KB) | HTML Full-text | XML Full-text

by ,  and
Sensors 2007, 7(12), 3156-3165; doi:10.3390/s7123156
Received: 1 November 2007; Accepted: 4 December 2007 / Published: 6 December 2007
Show/Hide Abstract | Cited by 5 | PDF Full-text (382 KB) | HTML Full-text | XML Full-text

by , , , ,  and
Sensors 2007, 7(11), 2929-2941; doi:10.3390/S7112929
Received: 18 October 2007; Accepted: 21 November 2007 / Published: 22 November 2007
Show/Hide Abstract | Cited by 15 | PDF Full-text (840 KB) | HTML Full-text | XML Full-text

by ,  and
Sensors 2007, 7(10), 2389-2401; doi:10.3390/s7102389
Received: 27 August 2007; Accepted: 10 October 2007 / Published: 17 October 2007
Show/Hide Abstract | Cited by 34 | PDF Full-text (2229 KB) | HTML Full-text | XML Full-text

by ,  and
Sensors 2007, 7(10), 2062-2079; doi:10.3390/s7102062
Received: 6 September 2007; Accepted: 26 September 2007 / Published: 3 October 2007
Show/Hide Abstract | Cited by 8 | PDF Full-text (1123 KB) | HTML Full-text | XML Full-text

by , , ,  and
Sensors 2007, 7(9), 1834-1845; doi:10.3390/s7091834
Received: 27 July 2007; Accepted: 6 September 2007 / Published: 7 September 2007
Show/Hide Abstract | Cited by 9 | PDF Full-text (362 KB) | HTML Full-text | XML Full-text

by , ,  and
Sensors 2007, 7(9), 1757-1765; doi:10.3390/s7091757
Received: 30 July 2007; Accepted: 4 September 2007 / Published: 5 September 2007
Show/Hide Abstract | Cited by 20 | PDF Full-text (173 KB) | HTML Full-text | XML Full-text

by , ,  and
Sensors 2007, 7(9), 1713-1719; doi:10.3390/s7091713
Received: 24 July 2007; Accepted: 27 August 2007 / Published: 3 September 2007
Show/Hide Abstract | Cited by 2 | PDF Full-text (308 KB) | HTML Full-text | XML Full-text

Last update: 4 March 2014

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