Special Issue "Sensors for Bioprocess Monitoring and Control"


A special issue of Sensors (ISSN 1424-8220). This special issue belongs to the section "Biosensors".

Deadline for manuscript submissions: 30 August 2014

Special Issue Editor

Guest Editor
Prof. Dr. Bernd Hitzmann
Department of Process Analysis and Cereal Technology, Institute of Food Science and Biotechnology, University of Hohenheim, Garbenstr. 23, 70599 Stuttgart, Germany
Website: https://www.uni-hohenheim.de/institution/fg-prozessanalytik-und-getreidetechnologie-8
E-Mail: Bernd.Hitzmann@uni-hohenheim.de
Phone: +49 711 459 23286
Fax: +49 711 459 23259
Interests: process analytical technologies, spectroscopic sensors, image analysis, biosensors, chemometrics, software sensors, observers, process modeling, process control algorithms, cereal technology

Special Issue Information

Dear Colleagues,

The monitoring of bioprocesses is still a challenging task. Without real time information of the actual state, an optimal process operation cannot be guaranteed. If cultivation processes are considered, one has to deal with a complex, non-linear, multi-parameter and time variant system. Therefore, to meet the requirements for bioprocesses supervision, advanced sensor techniques are necessary. Due to the increasing use of disposable bioreactors, the sensors for these applications must also be disposable or easy to connect to the reactor. If process variables cannot be measured directly, or are too costly or time-consuming to measure, then soft-sensors can be applied. Typically several raw measurements are used in combination with an empirical or theoretical model for the prediction of process variables.

For an optimal operation of a bioreactor, not only measurements are important but also the utilization of the information in a close loop control system. In recent years, many contributions have been published dealing with closed loop control of bioprocesses, but only a minority have actually been applied in real bioprocesses; mostly simulations are used. However, for these control systems, requirements such as stability and reliability for the measurement sensors are even more of a challenge.

Review articles as well as original research papers relating to the monitoring and control of bioprocesses are solicited with particular interest in papers concerning applications where the sensor information is directly used for bioprocess automation.

Prof. Dr. Bernd Hitzmann
Guest Editor


Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Sensors is an international peer-reviewed Open Access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs).


  • soft-sensors
  • cultivation process
  • process supervision
  • closed loop control
  • actuator

Published Papers

No papers have been published in this special issue yet.

Last update: 12 February 2014

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