Special Issue "Functional Nanohybrids for Drug Delivery"
A special issue of Pharmaceutics (ISSN 1999-4923).
Deadline for manuscript submissions: 30 January 2019
Nanomaterial-based drug delivery systems have been seen as a publicly-known strategy to improve therapeutic efficacy in cancer therapies. However, dense extracellular matrix and interstitial fluid pressure in the tumor suppress deep delivery and lead to inhomogeneous treatments. Not only able to accumulate at highly permeable peripheral blood vessels via enhanced permeability and retention (EPR) effects, nanohybrids should also be concerned with different functions to enhance drug delivery. Stimuli-response and functions of nanohybrids are two impressive manipulations for enhanced drug delivery. In addition, targeting moiety for specific diseases also shelters the mononuclear phagocyte system and promotes enhanced delivery. Therefore, after drug injection, obstacles from blood circulation, tumor accumulation, and penetrated delivery should be comprehensively considered, and thus multifunctional nanohybrids will be the ideal platforms for enhanced drug delivery. The development of new nanohybrids represents an important step in the field of drug delivery systems.
This Special Issue has the aim of highlighting current progress in the use of the multifunctional nanohybrids for enhanced drug delivery.Prof. Shang-Hsiu Hu
Prof. Chien-Wen Chang
Manuscript Submission Information
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- Drug delivery
- Cancer therapy
- Functional materials
- Triggered release