Special Issue "Sustainable Synthesis"
Deadline for manuscript submissions: 28 February 2019
Prof. Dr. Wei Zhang
The aim of the development of green and sustainable chemistry is to maximize the benefit of chemistry and chemical products introduced to human society, and minimize their side effects on the environment and public health. This Special Issue presents recent developments on green and sustainable techniques for organic synthesis. It covers following four areas: 1) catalysis reactions (metal-catalysis, organocatalysis, and biocatalysis; 2) new reactions and techniques (pot/atom/step economy reactions, C-H functionalization, flow chemistry, microwave, ultrasonic, photolysis, photoredox, mechanochemistry); 3) alternative solvents (biorenewable solvents, aqueous, ionic liquids, SC-CO2); and 4) CO2 and biomass-derived building blocks for synthesis.
Prof. Wei Zhang
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Pot, atom and step economic (SPAE) synthesis
- One-pot reactions
- Multicomponent reactions
- Cascade reactions
- Alternative solvents
- Biorenewable solvents
- Solvent-free reactions
- Metal catalysis
- C-H activation
- Biomass-derived building blocks
- CO2 as a synthon
- Photoredox reactions
- Photo reactions
- Microwave reactions
- Ultrasound reactions
- Recyclable reagents and catalysts
- Flow chemistry
The below list represents only planned manuscripts. Some of these manuscripts have not been received by the Editorial Office yet. Papers submitted to MDPI journals are subject to peer-review.
Type of the paper: Article
Tentative title: Immobilized gold(I) nanoparticles prepared from gold(III)-containing ionic
liquids on silica: application to the sustainable synthesis of propargylamines
Authors: Raquel Soengas,^a * Yolanda Navarro,^a María José Iglesias,^a Fernando López Ortiz^a *
Affiliations: a) Área de Química Orgánica, Research Centre CIAIMBITAL, Universidad de Almería, Ctra. Sacramento s/n, 04120, Almería, Spain
Abstract: Acycloaurated phosphinothioic amide gold(III) complex was supported on amorphous silica with the aid of an ionic liquid, [bmim]PF_6 . Gold(I) nanoparticles were formed in situ and subsequently immobilized on the SiO_2 -IL phase. The resulting immobilized AuNPs@SILP catalyst were highly efficient in promoting the solvent-free A^3 coupling reaction of alkynes, aldehydes and imines in high yields under solvent-free conditions, with a very low catalystloading and without the use of additives. Additionally, the AuNPs@SILP has good recyclability and can be reused at least five times in 98-80% yields. This synthetic method provides a green and low cost way to effectively synthetize propargylamines.
Title: Ionic liquid promoted three-component domino reaction of propargyl alcohols, carbon dioxide and 2-aminoethanols: A thermodynamically favourable synthesis of 2-oxazolidinones
Author: Shu-Mei Xia ^1 , Yu Song ^1 , Xue-Dong Li ^1 , Hong-Ru Li^*2, Liang-Nian He^1
1State Key Laboratory and Institute of Elemento-Organic Chemistry, College of Chemistry, Nankai University, Tianjin, 300071, P. R. China.
2College of Pharmacy, Nankai University, Tianjin 300353, P. R. China
3Correspondence: email@example.com; Tel.: +86-22-23503878
Abstract: To circumvent the thermodynamic limitation of the synthesis of oxazolidinones starting from 2-aminoethanols and CO_2 and realize incorporation CO_2 under atmospheric pressure, an ionic liquid facilitated three-component reaction of propargyl alcohols, CO_2 and 2-aminoethanols was developed to produce 2-oxazolidinones and equal amount of α-hydroxyl ketones. The ionic liquid structure, reaction temperature and reaction time were in detail investigated. And 15 mol% [TBDH][TFE] was found to be the most one in this study for this cascade reaction. Under atmospheric CO_2 , 2-aminoethanols with different substituents were successfully transformed to 2-oxazolidinones with moderate to excellent yield after 12 h reaction at 80 ºC.
Keywords: Ionic liquid; 2-oxazolidinone; 2-aminoethanol; propargyl alcohol; CO_2 ; α-hydroxyl ketones