Special Issue "Methods in Polyphenol Analysis"


A special issue of Molecules (ISSN 1420-3049).

Deadline for manuscript submissions: closed (30 November 2012)

Special Issue Editor

Guest Editor
Dr. Renato Bruni
The φ2 Laboratory of Phytochemicals in Physiology, Department of Functional and Evolutive Biology, University of Parma, Viale G. Usberti 11a, 43100 Parma, Italy
E-Mail: renato.bruni@unipr.it
Interests: phytochemical analysis by means of chromatographic and spectroscopic techniques: GC, GC-MS, HPLC, 13C, 1H-NMR; pharmacognostic; chemical and DNA-based quality control in herbal drugs and plant foods; biotic and abiotic factors affecting secondary metabolite production in edible and medicinal plants; biological and pharmacological activity of plant extracts; ethnopharmacology and ethnobotany

Special Issue Information

Dear Colleagues,

Polyphenolic substances are likely the most protean class of natural compounds and great challenges lie behind their study. They play a relevant role in plant ecophysiology, counteracting a wide range of biotic and abiotic factors and their chemical and biological plasticity reverberates in a plethora of applicative uses. Plant-derived polyphenols are in fact multi-purpose substances whose exploitation ranges from phytocosmetics to nutraceuticals, from medicinal and edible plants to pharmaceuticals, from pigments and dyes to fine chemicals and allelochemicals of agronomic value. As a consequence of that, for both ecological, environmental, plant, food and health sciences a proper knowledge of polyphenol variability, abundance and role represents a key feature. The analytical determination of these secondary metabolites in different matrices and the evaluation of their biological properties are of crucial relevance also in a number of industrial fields.
As these topics have been the focus of many recent technological improvements, contributions for this special issue, both in form of original research and review articles, may cover the development, validation or the improvement of any new applied method devoted to the chemical (chromatographic, spectroscopic, metabolomic, chemometric and sensorial), biochemical and biological evaluation of polyphenolic substances in any crude or processed plant material, biological fluid and product (including foods, drugs, biomasses, herbal products, dyes, animal feeds and agroindustrial wastes). The presented methods must demonstrate their applicability on real samples and not exclusively on standard substances. Fingerprinting methods capable to monitor polyphenols during different production processes, during storage in crude drugs and finished products and capable to elucidate their fate in vivo (in both animals, plants and environment) will be particularly welcome. Review articles must cover the state-of-the-art and trends in the analysis of specific sub-classes of polyphenolic substances or the perspectives regarding the applicability of definite techniques. Authors considering the submission of a review are kindly asked to provide in advance to the guest editor a brief outline of the subject matter of their work.
Manuscripts regarding new methods for the evaluation of polyphenol bioactivity are also suitable for submission. In particular, innovative protocols and methods based on chemical or biological systems for the evaluation of in vivo and in vitro bioactivities of pure polyphenols and/or polyphenol-rich products or extracts will be taken into consideration, on condition that they are properly characterized from a phytochemical standpoint.

Dr. Renato Bruni
Guest Editor


  • polyphenols
  • phytochemical analysis
  • chromatography
  • sectroscopy
  • quality control
  • fingerprinting
  • bioactivity

Published Papers (6 papers)

by , ,  and
Molecules 2012, 17(8), 9668-9682; doi:10.3390/molecules17089668
Received: 29 May 2012; in revised form: 1 August 2012 / Accepted: 3 August 2012 / Published: 13 August 2012
Show/Hide Abstract | Cited by 4 | PDF Full-text (367 KB)
abstract graphic

by , , , , , ,  and
Molecules 2012, 17(10), 12393-12405; doi:10.3390/molecules171012393
Received: 31 August 2012; in revised form: 13 September 2012 / Accepted: 15 October 2012 / Published: 22 October 2012
Show/Hide Abstract | Cited by 5 | PDF Full-text (398 KB) | HTML Full-text | XML Full-text
abstract graphic

by , , , , , ,  and
Molecules 2012, 17(12), 14821-14840; doi:10.3390/molecules171214821
Received: 16 November 2012; in revised form: 7 December 2012 / Accepted: 10 December 2012 / Published: 13 December 2012
Show/Hide Abstract | Cited by 10 | PDF Full-text (634 KB)

by , ,  and
Molecules 2013, 18(1), 1076-1100; doi:10.3390/molecules18011076
Received: 18 December 2012; in revised form: 7 January 2013 / Accepted: 14 January 2013 / Published: 16 January 2013
Show/Hide Abstract | Cited by 5 | PDF Full-text (588 KB)

by ,  and
Molecules 2013, 18(2), 2328-2375; doi:10.3390/molecules18022328
Received: 25 October 2012; in revised form: 10 January 2013 / Accepted: 31 January 2013 / Published: 19 February 2013
Show/Hide Abstract | Cited by 15 | PDF Full-text (600 KB)

by , ,  and
Molecules 2013, 18(4), 3859-3871; doi:10.3390/molecules18043859
Received: 27 December 2012; in revised form: 19 March 2013 / Accepted: 20 March 2013 / Published: 28 March 2013
Show/Hide Abstract | Cited by 2 | PDF Full-text (318 KB)

Last update: 4 March 2014

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