Special Issue "Methods in Polyphenol Analysis"
A special issue of Molecules (ISSN 1420-3049).
Deadline for manuscript submissions: closed (30 November 2012)
Dr. Renato Bruni
The φ2 Laboratory of Phytochemicals in Physiology, Department of Functional and Evolutive Biology, University of Parma, Viale G. Usberti 11a, 43100 Parma, Italy
Interests: phytochemical analysis by means of chromatographic and spectroscopic techniques: GC, GC-MS, HPLC, 13C, 1H-NMR; pharmacognostic; chemical and DNA-based quality control in herbal drugs and plant foods; biotic and abiotic factors affecting secondary metabolite production in edible and medicinal plants; biological and pharmacological activity of plant extracts; ethnopharmacology and ethnobotany
Polyphenolic substances are likely the most protean class of natural compounds and great challenges lie behind their study. They play a relevant role in plant ecophysiology, counteracting a wide range of biotic and abiotic factors and their chemical and biological plasticity reverberates in a plethora of applicative uses. Plant-derived polyphenols are in fact multi-purpose substances whose exploitation ranges from phytocosmetics to nutraceuticals, from medicinal and edible plants to pharmaceuticals, from pigments and dyes to fine chemicals and allelochemicals of agronomic value. As a consequence of that, for both ecological, environmental, plant, food and health sciences a proper knowledge of polyphenol variability, abundance and role represents a key feature. The analytical determination of these secondary metabolites in different matrices and the evaluation of their biological properties are of crucial relevance also in a number of industrial fields.
As these topics have been the focus of many recent technological improvements, contributions for this special issue, both in form of original research and review articles, may cover the development, validation or the improvement of any new applied method devoted to the chemical (chromatographic, spectroscopic, metabolomic, chemometric and sensorial), biochemical and biological evaluation of polyphenolic substances in any crude or processed plant material, biological fluid and product (including foods, drugs, biomasses, herbal products, dyes, animal feeds and agroindustrial wastes). The presented methods must demonstrate their applicability on real samples and not exclusively on standard substances. Fingerprinting methods capable to monitor polyphenols during different production processes, during storage in crude drugs and finished products and capable to elucidate their fate in vivo (in both animals, plants and environment) will be particularly welcome. Review articles must cover the state-of-the-art and trends in the analysis of specific sub-classes of polyphenolic substances or the perspectives regarding the applicability of definite techniques. Authors considering the submission of a review are kindly asked to provide in advance to the guest editor a brief outline of the subject matter of their work.
Manuscripts regarding new methods for the evaluation of polyphenol bioactivity are also suitable for submission. In particular, innovative protocols and methods based on chemical or biological systems for the evaluation of in vivo and in vitro bioactivities of pure polyphenols and/or polyphenol-rich products or extracts will be taken into consideration, on condition that they are properly characterized from a phytochemical standpoint.
Dr. Renato Bruni
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed Open Access monthly journal published by MDPI.
- phytochemical analysis
- quality control
Article: Evaluation of Flavonoid Contents and Antioxidant Capacity of the Aerial Parts of Common and Tartary Buckwheat Plants
Molecules 2012, 17(8), 9668-9682; doi:10.3390/molecules17089668
Received: 29 May 2012; in revised form: 1 August 2012 / Accepted: 3 August 2012 / Published: 13 August 2012| Download PDF Full-text (367 KB)
Molecules 2012, 17(10), 12393-12405; doi:10.3390/molecules171012393
Received: 31 August 2012; in revised form: 13 September 2012 / Accepted: 15 October 2012 / Published: 22 October 2012| Download PDF Full-text (398 KB) | Download XML Full-text
Article: Rapid and Comprehensive Evaluation of (Poly)phenolic Compounds in Pomegranate (Punica granatum L.) Juice by UHPLC-MSn
Molecules 2012, 17(12), 14821-14840; doi:10.3390/molecules171214821
Received: 16 November 2012; in revised form: 7 December 2012 / Accepted: 10 December 2012 / Published: 13 December 2012| Download PDF Full-text (634 KB)
Molecules 2013, 18(1), 1076-1100; doi:10.3390/molecules18011076
Received: 18 December 2012; in revised form: 7 January 2013 / Accepted: 14 January 2013 / Published: 16 January 2013| Download PDF Full-text (588 KB)
Molecules 2013, 18(2), 2328-2375; doi:10.3390/molecules18022328
Received: 25 October 2012; in revised form: 10 January 2013 / Accepted: 31 January 2013 / Published: 19 February 2013| Download PDF Full-text (600 KB)
Article: HPLC-DAD-ESI/MS Identification and Quantification of Phenolic Compounds in Ilex paraguariensis Beverages and On-Line Evaluation of Individual Antioxidant Activity
Molecules 2013, 18(4), 3859-3871; doi:10.3390/molecules18043859
Received: 27 December 2012; in revised form: 19 March 2013 / Accepted: 20 March 2013 / Published: 28 March 2013| Download PDF Full-text (318 KB)
The below list represents only planned manuscripts. Some of these manuscripts have not been received by the Editorial Office yet. Papers submitted to MDPI journals are subject to peer-review.
Type of Paper: Review
Title: Analysis of Phenolics in Foods
Author: Department of Plant and Food Sciences, Faculty of Agriculture and Environment, University of Sydney, NSW 2006, Australia; E-Mails: firstname.lastname@example.org; email@example.com; firstname.lastname@example.org
Abstract: Phenolic compounds are well-known phytochemicals found in all plants. This group of molecules consists of simple phenols, benzoic and cinnamic acids, coumarins, tannins, lignins, lignans and flavonoids. Substantial developments in research into the extraction, identification and quantification of phenolic compounds as medicinal and/or dietary molecules have occurred over the last 25 years. Organic solvent extraction is the main method used to extract phenolics. Traditional chemical procedures are used to detect the presence of total phenolics while spectrophotometric and chromatographic techniques are utilized to identify and quantify individual phenolic compounds. This review addresses the application of different methodologies for analysis of phenolic compounds in food, including recent technical developments in quantification of phenolics.
Type of Paper: Review
Title: Antimicrobial Susceptibility Testing of Plant Polyphenolic Compounds: Current Methods and Future Directions and Needs
Authors: Marina Bubonja-Sonje1,2 and Maja Abram 1,2
Affiliations: 1 Department of Clinical Microbiology, Clinical Hospital Rijeka, Faculty of Medicine, University of Rijeka, Rijeka, Croatia
2 Department of Microbiology and Parasitology, Faculty of Medicine, University of Rijeka, Rijeka, Croatia
Abstract: Due to growing incidences of drug-resistant pathogens the antimicrobial properties of plant-derived polyphenols have recently become of great interest. Numerous reports show that polyphenolic substances may have a role as potential antimicrobial substances. However, several factors can influence antimicrobial susceptibility testing, and results comparability is largely dependent on the techniques employed. In general, testing methods provide reliable results when used according to the standard procedures. Due to the absence of standards for investigations of antimicrobial efficacy of polyphenols different guidelines used in assessment of antimicrobial activity of antibiotics are being applied. Thus, there is a need for development of standard and universal methods in assessment of antimicrobial activity of polyphenolic compounds. Polyphenolic extraction method can additionally influence results of antimicrobial activity testing. Moreover, to provide more meaningful prediction of antimicrobial efficacy in vivo the information obtained in vitro is necessary to combine with pharmacokinetic and pharmacodynamic data. This paper reviews different methods used in the assessment of polyphenols antimicrobial efficacy and their spectrum of activity.
Last update: 4 February 2013