Special Issue "Methods in Polyphenol Analysis"
A special issue of Molecules (ISSN 1420-3049).
Deadline for manuscript submissions: closed (30 November 2012)
Dr. Renato Bruni
The φ2 Laboratory of Phytochemicals in Physiology, Department of Functional and Evolutive Biology, University of Parma, Viale G. Usberti 11a, 43100 Parma, Italy
Interests: phytochemical analysis by means of chromatographic and spectroscopic techniques: GC, GC-MS, HPLC, 13C, 1H-NMR; pharmacognostic; chemical and DNA-based quality control in herbal drugs and plant foods; biotic and abiotic factors affecting secondary metabolite production in edible and medicinal plants; biological and pharmacological activity of plant extracts; ethnopharmacology and ethnobotany
Polyphenolic substances are likely the most protean class of natural compounds and great challenges lie behind their study. They play a relevant role in plant ecophysiology, counteracting a wide range of biotic and abiotic factors and their chemical and biological plasticity reverberates in a plethora of applicative uses. Plant-derived polyphenols are in fact multi-purpose substances whose exploitation ranges from phytocosmetics to nutraceuticals, from medicinal and edible plants to pharmaceuticals, from pigments and dyes to fine chemicals and allelochemicals of agronomic value. As a consequence of that, for both ecological, environmental, plant, food and health sciences a proper knowledge of polyphenol variability, abundance and role represents a key feature. The analytical determination of these secondary metabolites in different matrices and the evaluation of their biological properties are of crucial relevance also in a number of industrial fields.
As these topics have been the focus of many recent technological improvements, contributions for this special issue, both in form of original research and review articles, may cover the development, validation or the improvement of any new applied method devoted to the chemical (chromatographic, spectroscopic, metabolomic, chemometric and sensorial), biochemical and biological evaluation of polyphenolic substances in any crude or processed plant material, biological fluid and product (including foods, drugs, biomasses, herbal products, dyes, animal feeds and agroindustrial wastes). The presented methods must demonstrate their applicability on real samples and not exclusively on standard substances. Fingerprinting methods capable to monitor polyphenols during different production processes, during storage in crude drugs and finished products and capable to elucidate their fate in vivo (in both animals, plants and environment) will be particularly welcome. Review articles must cover the state-of-the-art and trends in the analysis of specific sub-classes of polyphenolic substances or the perspectives regarding the applicability of definite techniques. Authors considering the submission of a review are kindly asked to provide in advance to the guest editor a brief outline of the subject matter of their work.
Manuscripts regarding new methods for the evaluation of polyphenol bioactivity are also suitable for submission. In particular, innovative protocols and methods based on chemical or biological systems for the evaluation of in vivo and in vitro bioactivities of pure polyphenols and/or polyphenol-rich products or extracts will be taken into consideration, on condition that they are properly characterized from a phytochemical standpoint.
Dr. Renato Bruni
- phytochemical analysis
- quality control