Special Issue "Expanding the Potential of Metabolomics for Under Investigated Organisms and in Drug Discovery"
Deadline for manuscript submissions: closed (31 March 2017)
Natural products (NPs) constitute an important part of our everyday diet; their components and nutritional/medicinal values have also been intensively studied for decades. The existence of NPs at minor levels in such a complex matrix, or being even labile, is expected, and isolation of such compounds still poses a challenge. The comparison of metabolite composition of biological systems (known as metabolomics) is now a mature field that has been increasingly applied to expedite natural products drug discovery. Metabolomics underlying emerging spectroscopic and informatics technologies has indeed demonstrated potential towards shorter drug discovery leading to a paradigm shift in NPs research. Metabolomics is rapidly evolving, with many novel techniques becoming available, i.e., MS imaging, HR-MAS NMR. The convergence of metabolomics and NPs discovery has also been demonstrated much more often from natural terrestrial origin mostly in planta, with much less evidence from other resources. It is expected that algae, fungi, sponges, sea corals, gut microbiota, etc., have an enormous potential to act as providers for novel bioactive metabolites. The integration of metabolomics towards facilitating the discovery and chemistry of plant derived NPs, is expected to be revealed from other organisms. In light of these urging topics, Molecules is introducing a new Special Issue on “Metabolomics” and its applications. This Special Issue shall include two general themes: The first is to focus on diverse range of metabolomics applications, many of which to be related to investigations in under investigated organisms. The second shall provide reports on novel experimental technologies in metabolomics or developments needed for the analysis of labile NP classes.
Prof. Mohamed A. Farag
Dr. Andrea Porzel
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- natural products
- drug discovery
- gut microbes
- pure shift NMR
- HR-MAS NMR
- hyperpolarization NMR
- MS imaging
- metabolites profiling