Special Issue "Biosynthesis and Biotransformation"
A special issue of Molecules (ISSN 1420-3049).
Deadline for manuscript submissions: closed (31 December 2013)
Dr. Ioulia Smonou
Department of Chemistry, University of Crete, Campus Voutes-Heraklion, 71003 Crete, Greece
Interests: biocatalysis-biotransformations in organic synthesis; asymmetric synthesis of bioactive compounds using biocatalytic methods; applied biocatalysis; mechanisms of organic reactions
The contribution of Biosynthesis and Biotransformation is of increasing importance as potential alternative methods toward the synthesis of useful metabolites and their commercial production. Plant secondary metabolites, the natural products, are very useful in food and pharmaceutical industry,but their production by total synthesis is not economical. Plant cell culture or hairy root culture technology can be used as alternative methodology for the synthesis of useful chemical compounds or for the transformation of natural products to a variety of compounds of high economical importance.
Moreover, biotransformations, where secondary metabolites as well as xenobiotic compounds can be used as substrates, has emerged as one of the major targets of biotechnological application, offering great innovative potential in the otherwise difficult or impossible stereospecific synthesis of important organic molecules. Biotransformation reactions catalyzed by plant cell cultures include oxidoreductions, hydroxylations, acylations, etc. This innovative methodology is of great importance for industrial application.
This Special Issue on Biosynthesis and Biotransformation will offer an attractive forum to present the potential of this technology. I strongly encourage authors to submit papers for this Special Issue, within the scope of Molecules. I hope that the topics covered will reflect the potential and the excitement of Biosynthesis and Biotransformation in the scientific community.
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed Open Access monthly journal published by MDPI.
- biosynthetic enzymes
- biosynthesis and Bacteria
- mechanistic studies
- biosynthesis of natural products
- enzymatic reactions
Article: Artichoke, Cynarin and Cyanidin Downregulate the Expression of Inducible Nitric Oxide Synthase in Human Coronary Smooth Muscle Cells
Molecules 2014, 19(3), 3654-3668; doi:10.3390/molecules19033654
Received: 13 January 2014; in revised form: 17 March 2014 / Accepted: 18 March 2014 / Published: 24 March 2014| Download PDF Full-text (439 KB) | Download XML Full-text
Review: The Remarkable Structural Diversity Achieved in ent-Kaurane Diterpenes by Fungal Biotransformations
Molecules 2014, 19(2), 1856-1886; doi:10.3390/molecules19021856
Received: 24 December 2013; in revised form: 5 February 2014 / Accepted: 6 February 2014 / Published: 10 February 2014| Download PDF Full-text (423 KB)
Molecules 2013, 18(11), 13812-13822; doi:10.3390/molecules181113812
Received: 8 September 2013; in revised form: 28 October 2013 / Accepted: 30 October 2013 / Published: 7 November 2013| Download PDF Full-text (245 KB)
Last update: 15 July 2013