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Special Issue "Selected Papers from the 30th International Symposium on the Chemistry of Natural Products and the 10th International Congress on Biodiversity (ISCNP30 and ICOB10)"

A special issue of Molecules (ISSN 1420-3049).

Deadline for manuscript submissions: 1 May 2019

Special Issue Editors

Guest Editor
Prof. Alexios-Leandros Skaltsounis

National and Kapodistrian University of Athens, School of Health Sciences, Department of Pharmacognosy and Chemistry of Natural Products, Athens, Greece
Website | E-Mail
Interests: “Green” chemistry and large-scale extraction of high added value natural products; Isolation of natural products leads; Identification and structure elucidation of natural products; Semi- and total- synthesis of natural products; Characterisation of natural extracts; Design and synthesis of new molecules with pharmacological interest; Structure-activity relationships
Guest Editor
Prof. Emmanuel Mikros

National and Kapodistrian University of Athens, School of Health Sciences, Department of Pharmaceutical Chemistry, Athens, Greece
Website | E-Mail
Interests: Molecular Structure Analysis of biologically active molecules; N.M.R. spectroscopy and Molecular Calculations; Ligand-Protein Interactions monitored by NMR Spectroscopy and Molecular Modeling; Peptides and Natural products structural studies using 2D NMR spectroscopy; Structure Based Drug Design, In Silico screening; NMR based Metabonomics
Guest Editor
Assist. Prof. Maria Halabalaki

National and Kapodistrian University of Athens, School of Health Sciences, Department of Pharmacognosy and Chemistry of Natural Products, Athens, Greece
Website | E-Mail
Interests: Separation and purification of natural products; Structure elucidation of natural products; Quantitative and qualitative methods for characterization of natural extracts ; LC-MS based dereplication methods; NMR and LC-MS-based metabolomics approaches; LC-MS based analysis of human samples (plasma, urine, faeces)

Special Issue Information

Dear Colleagues,

On behalf of the International Union of Pure and Applied Chemistry (IUPAC), it is our privilege and special pleasure to invite you to the 30th International Symposium on the Chemistry of Natural Products and the 10th International Congress on Biodiversity (ISCNP30 and ICOB10), which will be held 25–29 November, 2018, in Athens, Greece

We sincerely believe that the IUPAC symposium in Athens will bring together scientists from all over the world in order to contribute in our better knowledge and understanding of the role of natural products in drug discovery, material science, nutrition and applied chemistry. Through a careful selection of speeches from established scientists, the addition of emerging topics from young group leaders, and the participation of young scientists through several travel fellowships, we aim to shed light into recent advances in natural products.

Nature has developed an enormous diversity during millions of years of evolution. It is estimated that in our planet exist around 30 million insects, 1.5 million algae, 1.5 million fungi, 1 million animals and 400,000 plant species. Green plants represent almost the 15% of the living organisms of our planet. It is historically proven that the green plants were facilitating the mankind significantly and were assisting its survival and progress. Humans, from the beginning of their existence on Earth, have been using plants extensively for several purposes, such as food, clothes, weapons, tools, poisons, medicines, etc. Despite their great importance, only a small proportion, approximately 10% of the classified ones, have been investigated and chemically characterized. All of these species coexist in ecosystems and interact with each other in several ways. All organisms share a similar biochemistry necessary for a living cell. They produce a wide variety of so-called “secondary metabolites” or “small molecules”.

Secondary metabolites are organic compounds characterized by small molecular weight that are not directly involved in the normal growth, development or reproduction of organisms. Unlike primary metabolites (peptides, proteins, lipids, carbohydrates), the absence of secondary metabolites does not result in immediate death, but rather in long-term impairment of an organism's survivability/fecundity or aesthetics, or perhaps in no significant change at all. Secondary metabolites are often restricted to a narrow set of species within a phylogenetic group. The function or importance of these compounds to the organism is usually of an ecological nature, as they are used as defenses against predators, parasites and diseases, for interspecies competition, and to facilitate the reproductive processes (coloring agents, attractive smells, etc.). Since these compounds are usually restricted to a much more limited group of organisms, they have long been of prime importance in taxonomic research.

Plant-derived small molecules are usually candidates for drugs, cosmetics or other technological developments, directly, or as an inspiration for synthetic products. The first scientific area that was motivated and approached natural small molecules systematically was medicine. For a long period, up to 1960s, the structural studies of natural products served as the principle driving force for drug discovery and still constitute a prolific source for novel leads and pharmacophores for medicinal chemistry. More than 50% of all New Chemical Entities (NCEs) introduced into pharmacotherapy over the period 1982–2002 were derived directly or indirectly from natural products. Subsequent to medicine, many other scientific areas, such as cosmetic science, biotechnology, and agriculture, came closer to small molecules in order to explore their capabilities for other targets.

In light of these premises, this Special Issue aims to collect original research articles and reviews on the chemistry of natural products, the evaluation of their pharmacological and biological properties, natural compounds of marine ecosystems, separation and extraction methodologies of natural sources, as well as natural products related to material science. Moreover, contributions in metabolomics (metabolic profiling, fingerprinting), dereplication, phytochemical analysis, as well as on the authenticity, traceability, and safety aspects of plant-based and food products are greatly welcome. Manuscripts related to medicinal chemistry and the synthesis of organic molecules, bioengineering and combinatorial biosynthesis, as well as studies dealing with biodiversity, chemical ecology and nutrition are included in within the scope of this Special Issue

We hope that you may consider the opportunity to contribute to this effort, which will hopefully provide a collection of manuscripts serving as a reference for the scientists in the field and motivate new ones to enter in the area of Natural Products Chemistry research.

Prof. Alexios-Leandros Skaltsounis
Prof. Emmanuel Mikros
Assist. Prof. Maria Halabalaki
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • Chemistry of natural products
  • Bioactive natural products
  • Natural compounds from marine organisms
  • Medicinal chemistry and synthesis
  • Separation and extraction methodologies
  • Metabolomics and phytochemical analysis
  • Authenticity, traceability, safety of plant-based products
  • Natural products in material science
  • Bioengineering and combinatorial biosynthesis
  • Biodiversity and nutrition
  • Biodiversity and chemical ecology

Published Papers

This special issue is now open for submission.
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