Dear Colleagues,

Microfluidic technology has provided powerful high-throughput screening platforms to simultaneously perform a large number of chemical, genetic, or pharmacological tests, thus allowing rapid identification of chemical compounds, antibodies, and genes responsible for modulation of a particular biomolecular pathway. Many microfluidic devices have shown great potential to aid drug discovery and target validation, and expedite functional genomics and phenomics studies. In particular, some devices have already started to provide researchers and even pharmaceutical industry with an increasing number of molecular targets for therapeutic intervention, thus having increasing academic, social and economic impacts. This Special Issue seeks to contribute to this emergent field by featuring research papers, communications, opinion papers, and review articles from methodological and disciplinary perspectives, focusing on microfluidic devices enabled high throughput assays for biological, chemical, and environmental conditions of single cells and multicellular organisms. Of particular interest is the focus on system automation and miniaturization towards high-throughput approaches to gaining deeper insight into the effects and functions of molecules and the correlation between genomic and phenomic variables.

Prof. Dr. Liang Dong
Guest Editor

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• microfluidics
• lab on a chip
• high throughput screening
• single cells studies
• multicellular organisms