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Special Issue "State-of-the-Art Materials Science in Italy 2017"

A special issue of Materials (ISSN 1996-1944).

Deadline for manuscript submissions: 31 March 2018

Special Issue Editors

Guest Editor
Prof. Dr. Carla Renata Arciola

1.Head of the Research Unit on Implant Infections, Rizzoli Orthopaedic Institute, Via di Barbiano 1/10, 40136 Bologna, Italy
2. Professor of General Pathology, Medical School, University of Bologna, Via S. Giacomo 14, 40126 Bologna, Italy
Website | E-Mail
Interests: anti-adhesive surfaces; Anti-biofilm agents; Anti-biofouling materials; Antibiotic-loaded biomaterials; Anti-infective materials; Anti-infective tissue regeneration membranes; Bioactive antibacterial coatings; Materials delivering antimicrobials; Covalent conjugation of antimicrobial peptides; (GTR/GBR) membrane with anti-infective properties; Implant infections; Multilayer antibacterial films; Periprosthetic infections; Photocatalytic coatings for hygienic surfaces; Technologies and nano-technologies for infection-resistant surfaces
Guest Editor
Dr. Marco Salerno

IIT – Italian Institute of Technology, Nanophysics Department, 16163 Genova Italy
Website | E-Mail
Interests: dental materials; atomic force microscopy; anodic porous alumina; composites; nanoindentation; surface treatment of dental implants; nanoporous oxides of valve metals

Special Issue Information

Dear colleagues,

In Italy, the materials science is protagonist of a remarkable development, which can be attributed to several factors including the excellence of Italian academic and industrial research, as well as to the excellent capacity of Italian companies to turn innovation into valuable products. 

These advancements are particularly notable in the health area. The biotech companies in Italy are almost 500 and more than half of these are companies that dedicate over 75% of their total R & D investment in biotech researches. In particular, more than 250 companies are engaged in research of new therapeutic and diagnostic tools, the core activity being the research and applications of nanostructured materials.

In the academic area, the interest on materials and biomaterials is oriented on both research and high formation. An increasing number of research papers in the field of new biomaterials is yearly published and new PhD courses on these items are activated in Italian Universities.

For example, in the field of medical tissue engineering, interesting hot topics are presently cell-based biomaterials and nanoparticles coatings aiming to repair bone and joint defects, or biomaterials able to tune the inflammatory response. Additionally, multifunctional polymeric nanoconstructs for drug delivery and imaging open new perspectives in the field of nano-oncology. Similarly, an active field of development for biomaterials is that of dental research, from restorative composites or glass-ionomer cements, to bioactive implant materials.

On the industrial side, materials science is producing innovative materials for food packaging, aiming to avoid the migration of toxic substances from the envelop to the food or to avoid water and oil leakage from the food to the container. 

Additionally, vegetable substances are of interest in the field of materials not only as food to be protected but also as a source for bioplastics, such as for raw starch and cellulose but also for by-products of the agricultural foods as is the case of tomato skin.

Polymer fibers are increasingly employed, particularly in the field of innovative biomedical devices for wound care. For example, electrospun fibers can be designed to be ultrafine and to give mechanical flexibility and conformability to non-woven materials for wound dressing and coverage of the injured tissues, protection against infections and dehydration, transport of nutrients, retention of moisture and absorption of exudates. New materials, possibly modified by hybrid formulations including inorganic functional materials such as graphene or other carbon-based nanofillers, should guarantee adhesion, proliferation and differentiation of cells during tissue regeneration and delivery of drugs, as anti-inflammatory and antimicrobial agents. Preventing infection is the main focus on wound care. In this connection, essential oils or other natural compounds from plants appear promising additives to be encapsulated in advanced biomedical devices.

Besides the mentioned innovative materials, other innovative issues are welcome.

This special issue is aimed at collecting excellent papers that will be of interest to scholars in the field.

Prof. Dr. Carla Renata  Arciola
Dr. Marco  Salerno
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Materials is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1500 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • 3D printed scaffolds

  • Alloys and intermetallics

  • Anti-fouling and bacteria repelling surfaces

  • Bactericidal coatings

  • Anti-bacterial surfaces

  • Anti-biofilm surfaces

  • Anti-infective biomaterials

  • Anti-infective catheters

  • Phytocompounds for anti-infective and anti-inflammatory biomaterials

  • Infection-resistant surfaces

  • Nanocapsules

  • Nanoparticle-mediated delivery systems

  • Bioactive implant materials

  • Biomaterials doped with anti-inflammatory agents

  • Biomaterials in bone repair

  • Biomaterials in oncology

  • Biomaterials in tissue engineering

  • Biomaterials technologies for antimicrobial properties

  • Biomaterials with wound-healing properties

  • Bioresorbable materials

  • Carbon based nanomaterials

  • Cell-based biomaterials

  • Colloids

  • Electrospun scaffolds

  • Green synthesis of metal nanoparticles

  • Hierarchical material structures and metamaterials

  • Hyaluronic Acid-based scaffolds for cartilage repair

  • Multifunctional polymeric nanoconstructs for drug delivery

  • Multilayered biomaterials for osteochondral regeneration

  • Nanocoatings

  • Nanomaterials

  • Nanosized delivery systems

  • Natural phenolpolymers: food and health applications

  • Oxides and ceramics

  • Phytofabricated biomaterials

  • Polymer-based biosensors

  • Polymers and composites

  • Porous materials

  • Restorative composites in dentistry

  • Scaffold fixation by magnetic forces

  • Scaffold supporting osteogenic differentiation of bone marrow cells

  • Scaffold to capture and kill cancer cells

  • Scaffolds for blood vessel regeneration

  • Self-assembled and self-organized materials

  • Silver-coated prosthesis in oncological surgery

  • Substitutes for articular cartilages

  • Thin films and coatings

Published Papers (2 papers)

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Research

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Open AccessArticle In Vitro Effectiveness of Microspheres Based on Silk Sericin and Chlorella vulgaris or Arthrospira platensis for Wound Healing Applications
Materials 2017, 10(9), 983; doi:10.3390/ma10090983
Received: 5 July 2017 / Revised: 10 August 2017 / Accepted: 21 August 2017 / Published: 23 August 2017
PDF Full-text (4905 KB) | HTML Full-text | XML Full-text
Abstract
Some natural compounds have recently been widely employed in wound healing applications due to their biological properties. One such compound is sericin, which is produced by Bombix mori, while active polyphenols, polysaccharides and proteins are synthetized by Chlorella vulgaris and Arthrospira platensis
[...] Read more.
Some natural compounds have recently been widely employed in wound healing applications due to their biological properties. One such compound is sericin, which is produced by Bombix mori, while active polyphenols, polysaccharides and proteins are synthetized by Chlorella vulgaris and Arthrospira platensis microalgae. Our hypothesis was that sericin, as an optimal bioactive polymeric carrier for microencapsulation process, could also improve the regenerative effect of the microalgae. A solvent-free extraction method and spray drying technique were combined to obtain five formulations, based on algal extracts (C. vulgaris and A. platensis, Chl and Art, respectively) or silk sericin (Ser) or their mixtures (Chl-Ser and Art-Ser). The spray drying was a suitable method to produce microspheres with similar dimensions, characterized by collapsed morphology with a rough surface. Art and Art-Ser showed higher antioxidant properties than other formulations. All microspheres resulted in cytocompatibility on fibroblasts until 1.25 mg/mL and promoted cell migration and the complete wound closure; this positive effect was further highlighted after treatment with Art and Art-Ser. To our surprize the combination of sericin to Art did not improve the microalgae extract efficacy, at least in our experimental conditions. Full article
(This article belongs to the Special Issue State-of-the-Art Materials Science in Italy 2017)
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Review

Jump to: Research

Open AccessReview Update on Monoterpenes as Antimicrobial Agents: A Particular Focus on p-Cymene
Materials 2017, 10(8), 947; doi:10.3390/ma10080947
Received: 25 July 2017 / Revised: 8 August 2017 / Accepted: 11 August 2017 / Published: 15 August 2017
PDF Full-text (426 KB) | HTML Full-text | XML Full-text
Abstract
p-Cymene [1-methyl-4-(1-methylethyl)-benzene] is a monoterpene found in over 100 plant species used for medicine and food purposes. It shows a range of biological activity including antioxidant, anti-inflammatory, antinociceptive, anxiolytic, anticancer and antimicrobial effects. This last property has been widely investigated due to the
[...] Read more.
p-Cymene [1-methyl-4-(1-methylethyl)-benzene] is a monoterpene found in over 100 plant species used for medicine and food purposes. It shows a range of biological activity including antioxidant, anti-inflammatory, antinociceptive, anxiolytic, anticancer and antimicrobial effects. This last property has been widely investigated due to the urgent need for new substances with antimicrobial properties, to be used to treat communicable diseases whose diffusion in developed countries has been facilitated by globalization and the evolution of antimicrobial resistance. This review summarizes available scientific data, as reported by the most recent studies describing the antimicrobial activity of p-cymene either alone, or as the main component of plant extracts, as well as addressing the mechanisms of action of cymenes as antimicrobial agents. While p-cymene is one of the major constituents of extracts and essential oils used in traditional medicines as antimicrobial agents, but considering the limited data on its in vivo efficacy and safety, further studies are required to reach a definitive recommendation on the use and beneficial effects of p-cymene in human healthcare and in biomedical applications as a promising candidate to functionalize biomaterials and nanomaterials. Full article
(This article belongs to the Special Issue State-of-the-Art Materials Science in Italy 2017)
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