Special Issue "AML in the Molecular Age: From Biology to Clinical Management"


A special issue of Journal of Clinical Medicine (ISSN 2077-0383).

Deadline for manuscript submissions: closed (20 September 2014)

Special Issue Editors

Guest Editor
Dr. Celalettin Ustun
Division of Hematology, Oncology and Transplantation, University of Minnesota, 420 Delaware Street SE, MMC 480 Minneapolis, MN 55455, USA
Website: http://www.dom.umn.edu/hematology-oncology-and-transplantation/faculty/celalettin-ustun/index.htm
E-Mail: custun@umn.edu
Phone: +612 624 5109
Fax: +612 625 6919
Interests: AML; elderly AML; alloHCT; infectious complications; systemic mastocytosis

Guest Editor
Dr. Lucy A. Godley
Section of Hematology/Oncology, Department of Medicine, The University of Chicago, 5841 S. Maryland Avenue, MC 2115, Chicago, IL 60637, USA
Website: http://www.uchospitals.edu/physicians/lucy-godley.html
E-Mail: lgodley@medicine.bsd.uchicago.edu
Phone: +773 702 4140
Fax: +773 702 9268
Interests: DNA methylation; hydroxymethylation; inherited susceptibility to hematopoietic malignancies

Special Issue Information

Dear Colleagues,

We appreciate your willingness to contribute an article to the upcoming Special Issue of the Journal of Clinical Medicine, which will focus on “AML in the Molecular Age: From Biology to Clinical Management”. In this Special Issue, we aim to discuss important scientific and clinical ongoing activities in AML. Scientific subjects will include articles concerning the epigenetic mechanisms of disease/therapy as well as the role of the immune system in AML. Very interesting and uncommon subjects will include discussions of extramedullary disease and evaluations of the central nervous system by various imaging techniques. Experts will describe the role of hypomethylating agents in the management of AML and currently emerging and promising investigational therapies. Clinical success relies greatly on supportive therapy, and we will discuss supportive therapy, including infection prophylaxis. Allogeneic hematopoietic stem cell transplantation remains the most effective measure for curing aggressive AML, and a variety of topics will be considered: donor selection, age of recipient, which has been increasing seemingly without limit; therefore, recipient/donor assessments are more important than ever in the aging population. Alternative donor use (e.g., cord blood and haploidentical individuals) has been increasing dramatically; when and who should be considered, what is being investigated? With significant changes occurring with respect to both donors and recipients, the pros and cons of using of anti-thymocyte globulin use in conditioning regimens will be also described.
We have included an overall outline here for your review and ask that you forward to us your final title by 20 August, 2014. We remind you that there will be NO page charges or extra charges for color figures. Articles will be due to us on September 20, 2014

Once again, we look forward to your participation.
With best regards,

Dr. Celalettin Ustun
Dr. Lucy A. Godley
Guest Editors


Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed Open Access quarterly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. For the first couple of issues the Article Processing Charge (APC) will be waived for well-prepared manuscripts. English correction and/or formatting fees of 250 CHF (Swiss Francs) will be charged in certain cases for those articles accepted for publication that require extensive additional formatting and/or English corrections.


  • hypomethylating agents
  • novel therapy
  • epigenetics
  • allogeneic hematopoietic cell transplantation
  • T cell depletion
  • umbilical cord blood transplantation

Published Papers (1 paper)

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p. 1466-1489
by , ,  and
J. Clin. Med. 2014, 3(4), 1466-1489; doi:10.3390/jcm3041466
Received: 21 September 2014; in revised form: 27 November 2014 / Accepted: 28 November 2014 / Published: 15 December 2014
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Last update: 19 March 2014

J. Clin. Med. EISSN 2077-0383 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert