Special Issue "Nanotoxicology and Lung Diseases"

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A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Toxicology".

Deadline for manuscript submissions: closed (15 October 2014)

Special Issue Editor

Guest Editor
Prof. Dr. James C. Bonner

Department of Biological Sciences, North Carolina State University, Raleigh, North Carolina, 27695, USA
Website: http://bonnerlab.wordpress.ncsu.edu
Interests: cellular and molecular mechanisms through which toxic environmental agents cause lung diseases; especially pulmonary fibrosis and asthma; lung fibrosis; asthma; nanotoxicology; metals; particles; fibers

Special Issue Information

Dear Colleagues,

The nanotechnology industry is rapidly developing, resulting in the production of a variety of engineered nanomaterials (ENMs) for a variety of applications. These ENMs include carbon nanotubes and metal or metal oxide nanoparticles such as zinc, titanium, cerium and silver that are incorporated into consumer products or encountered in occupational settings. Some of these novel engineered nanostructures represent a potential human health risk, due to the possibility of inhalation exposure and evidence that the lung, as well as other systemic sites, are targets for hazardous effects. Articles in this special issue will address cutting edge research aimed at elucidating the mechanisms through which ENMs cause pulmonary disease in rodents after lung exposure. Inhalation studies in rodents show that ENMs deposit within the distal regions in the lungs and cause inflammation, fibrosis, or alter immune responses. Because novel engineering methodology is resulting in the production of an increasing complexity of ENM structures that vary in toxicological activity, this issue will also address high content screening for the development of structure-activity relationships relevant to inhalation toxicity and safer design of nanoparticles. This will include exploration of factors that mediate toxic effects such as high aspect ratio, durability, and residual metal content. Finally, we will address how susceptibility factors, both genetic and environmental, determine pulmonary and systemic toxicity to ENMs.

Prof. Dr. James C. Bonner
Guest Editor

Submission:

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed Open Access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1600 CHF.

Keywords

  • nanoparticles
  • lung
  • toxicity
  • asthma
  • fibrosis
  • immunity

Published Papers (13 papers)

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Displaying article 1-13
p. 3474-3492
by , , , , , ,  and
Int. J. Mol. Sci. 2015, 16(2), 3474-3492; doi:10.3390/ijms16023474
Received: 11 October 2014 / Revised: 6 January 2015 / Accepted: 30 January 2015 / Published: 4 February 2015
Show/Hide Abstract | Cited by 3 | PDF Full-text (963 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Nanotoxicology and Lung Diseases)
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p. 40-48
by ,  and
Int. J. Mol. Sci. 2015, 16(1), 40-48; doi:10.3390/ijms16010040
Received: 14 October 2014 / Accepted: 15 December 2014 / Published: 23 December 2014
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(This article belongs to the Special Issue Nanotoxicology and Lung Diseases)
p. 23936-23974
by , ,  and
Int. J. Mol. Sci. 2014, 15(12), 23936-23974; doi:10.3390/ijms151223936
Received: 15 October 2014 / Revised: 26 November 2014 / Accepted: 15 December 2014 / Published: 22 December 2014
Show/Hide Abstract | Cited by 6 | PDF Full-text (4802 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Nanotoxicology and Lung Diseases)
p. 22258-22278
by  and
Int. J. Mol. Sci. 2014, 15(12), 22258-22278; doi:10.3390/ijms151222258
Received: 20 September 2014 / Revised: 31 October 2014 / Accepted: 24 November 2014 / Published: 3 December 2014
Show/Hide Abstract | Cited by 17 | PDF Full-text (728 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Nanotoxicology and Lung Diseases)
p. 17577-17600
by , ,  and
Int. J. Mol. Sci. 2014, 15(10), 17577-17600; doi:10.3390/ijms151017577
Received: 21 February 2014 / Revised: 25 August 2014 / Accepted: 25 August 2014 / Published: 29 September 2014
Show/Hide Abstract | Cited by 6 | PDF Full-text (3462 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Nanotoxicology and Lung Diseases)
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p. 7444-7461
by , , , , , , , , , , , , ,  and
Int. J. Mol. Sci. 2014, 15(5), 7444-7461; doi:10.3390/ijms15057444
Received: 6 March 2014 / Revised: 11 April 2014 / Accepted: 15 April 2014 / Published: 29 April 2014
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(This article belongs to the Special Issue Nanotoxicology and Lung Diseases)
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p. 7158-7182
by  and
Int. J. Mol. Sci. 2014, 15(5), 7158-7182; doi:10.3390/ijms15057158
Received: 17 February 2014 / Revised: 28 March 2014 / Accepted: 9 April 2014 / Published: 25 April 2014
Show/Hide Abstract | Cited by 12 | PDF Full-text (851 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Nanotoxicology and Lung Diseases)
p. 6815-6830
by ,  and
Int. J. Mol. Sci. 2014, 15(4), 6815-6830; doi:10.3390/ijms15046815
Received: 20 February 2014 / Revised: 25 March 2014 / Accepted: 9 April 2014 / Published: 22 April 2014
Show/Hide Abstract | Cited by 14 | PDF Full-text (2346 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Nanotoxicology and Lung Diseases)
p. 6072-6085
by , , , , , , , , ,  and
Int. J. Mol. Sci. 2014, 15(4), 6072-6085; doi:10.3390/ijms15046072
Received: 12 February 2014 / Revised: 25 March 2014 / Accepted: 27 March 2014 / Published: 10 April 2014
Show/Hide Abstract | Cited by 5 | PDF Full-text (2072 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Nanotoxicology and Lung Diseases)
p. 5852-5873
by  and
Int. J. Mol. Sci. 2014, 15(4), 5852-5873; doi:10.3390/ijms15045852
Received: 22 January 2014 / Revised: 28 March 2014 / Accepted: 28 March 2014 / Published: 8 April 2014
Show/Hide Abstract | Cited by 29 | PDF Full-text (377 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Nanotoxicology and Lung Diseases)
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p. 4795-4822
by  and
Int. J. Mol. Sci. 2014, 15(3), 4795-4822; doi:10.3390/ijms15034795
Received: 3 December 2013 / Revised: 24 February 2014 / Accepted: 3 March 2014 / Published: 18 March 2014
Show/Hide Abstract | Cited by 22 | PDF Full-text (1176 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Nanotoxicology and Lung Diseases)
p. 878-894
by , , , , , , , ,  and
Int. J. Mol. Sci. 2014, 15(1), 878-894; doi:10.3390/ijms15010878
Received: 11 December 2013 / Revised: 26 December 2013 / Accepted: 3 January 2014 / Published: 9 January 2014
Show/Hide Abstract | Cited by 9 | PDF Full-text (320 KB) | HTML Full-text | XML Full-text | Supplementary Files
(This article belongs to the Special Issue Nanotoxicology and Lung Diseases)
p. 23858-23871
by , , , , , , ,  and
Int. J. Mol. Sci. 2013, 14(12), 23858-23871; doi:10.3390/ijms141223858
Received: 10 October 2013 / Revised: 14 November 2013 / Accepted: 15 November 2013 / Published: 6 December 2013
Show/Hide Abstract | Cited by 4 | PDF Full-text (324 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Nanotoxicology and Lung Diseases)
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Last update: 31 March 2014

Int. J. Mol. Sci. EISSN 1422-0067 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert