Special Issue "Biodegradability of Materials in Biomedical Applications 2011"

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A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Material Sciences and Nanotechnology".

Deadline for manuscript submissions: closed (31 May 2011)

Special Issue Editors

Guest Editor
Prof. Dr. Aldo R. Boccaccini
Institute of Biomaterials, Department of Materials Science and Engineering, University of Erlangen-Nuremberg, 91058 Erlangen, Germany; Visiting Professor, Department of Materials, Imperial College London, London SW7 2BP, UK
Website: http://www.biomat.techfak.uni-erlangen.de
E-Mail: aldo.boccaccini@ww.uni-erlangen.de
Phone: +49 9131 85 28601
Fax: +49 9131 85 28602
Interests: biomaterials; porous materials; scaffolds; tissue engineering; bioactive glasses; composite materials; waste recycling; carbon nanotubes; electrophoretic deposition; vascularization; bioceramics; biofabrication; bioactive coatings; drug delivery

Guest Editor
Prof. Dr. Showan N. Nazhat
Department of Mining and Materials Engineering, McGill University, Montreal, Canada
E-Mail: showan.nazhat@mcgill.ca

Special Issue Information

Dear Colleagues,

New generation biomaterials should be able to stimulate specific cellular responses at the molecular level, moving from the concept of inertness to one of bioactivity, e.g. positive interaction at the biomaterial-tissue interface. In many cases the body needs only the temporary presence of a device or implant, in which case fully or partially biodegradable materials are better alternatives than biostable materials. The ideal biodegradable material – polymer, ceramic, metal or composite - should be biocompatible, provide adequate initial mechanical fixation, controllably degradable, and should ultimately be replaced by the regenerated tissue.

A wide range of biodegradable materials is being continuously investigated for biomedical applications, which include traditional and advanced biodegradable polymers, bioceramics and composites as well as a small group of metals and alloys based on magnesium.

Typical applications and research areas of biodegradable polymers include surgery sutures, wound dressing, antibacterial coatings, fixation devices, tissue engineering scaffolds as well as drug and cell delivery platforms. Current research focuses also on the development of biodegradable composites combining synthetic or natural biodegradable polymers and bioactive inorganic fillers, e.g. bioactive glasses and calcium phosphate ceramics, which mimic the structural characteristics of the natural extracellular matrix. Magnesium alloys are promising candidates for several structural biomedical applications due to their degradation ability combined with appropriate mechanical properties as well as good biocompatibility and are being proposed as cardiovascular stents, bone fixation devices and porous bone repair materials.

The present combined special issue in IJMS/Materials will include papers authored by researchers around the world reporting on cutting-edge results in the broad field of biodegradable materials for biomedical applications.

Prof. S. N. Nazhat
Prof. A. R. Boccaccini
Guest Editors

Keywords

  • biodegradable polymers
  • magnesium alloys
  • bioactive glasses
  • calcium phosphates
  • composites
  • tissue engineering
  • drug delivery
  • sutures
  • wound dressing
  • coatings
  • degradable stents

Related Special Issue

Published Papers (7 papers)

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Displaying article 1-7
p. 6597-6618
by , , , ,  and
Int. J. Mol. Sci. 2011, 12(10), 6597-6618; doi:10.3390/ijms12106597
Received: 27 June 2011; in revised form: 24 September 2011 / Accepted: 28 September 2011 / Published: 10 October 2011
Show/Hide Abstract | Cited by 2 | PDF Full-text (1309 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Biodegradability of Materials in Biomedical Applications 2011)
p. 4294-4314
by , , , ,  and
Int. J. Mol. Sci. 2011, 12(7), 4294-4314; doi:10.3390/ijms12074294
Received: 23 May 2011; in revised form: 27 June 2011 / Accepted: 27 June 2011 / Published: 4 July 2011
Show/Hide Abstract | Cited by 7 | PDF Full-text (862 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Biodegradability of Materials in Biomedical Applications 2011)
p. 4250-4270
by  and
Int. J. Mol. Sci. 2011, 12(7), 4250-4270; doi:10.3390/ijms12074250
Received: 14 April 2011; in revised form: 15 June 2011 / Accepted: 19 June 2011 / Published: 29 June 2011
Show/Hide Abstract | Cited by 55 | PDF Full-text (827 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Biodegradability of Materials in Biomedical Applications 2011)
p. 3857-3870
by , ,  and
Int. J. Mol. Sci. 2011, 12(6), 3857-3870; doi:10.3390/ijms12063857
Received: 5 May 2011; in revised form: 30 May 2011 / Accepted: 3 June 2011 / Published: 10 June 2011
Show/Hide Abstract | Cited by 2 | PDF Full-text (597 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Biodegradability of Materials in Biomedical Applications 2011)
p. 3394-3408
by , , , ,  and
Int. J. Mol. Sci. 2011, 12(6), 3394-3408; doi:10.3390/ijms12063394
Received: 13 April 2011; in revised form: 18 May 2011 / Accepted: 19 May 2011 / Published: 25 May 2011
Show/Hide Abstract | Cited by 6 | PDF Full-text (659 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Biodegradability of Materials in Biomedical Applications 2011)
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p. 252-265
by , , , , ,  and
Int. J. Mol. Sci. 2011, 12(1), 252-265; doi:10.3390/ijms12010252
Received: 28 November 2010; in revised form: 26 December 2010 / Accepted: 1 January 2011 / Published: 5 January 2011
Show/Hide Abstract | Cited by 15 | PDF Full-text (436 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Biodegradability of Materials in Biomedical Applications 2011)
p. 3298-3322
by , ,  and
Int. J. Mol. Sci. 2010, 11(9), 3298-3322; doi:10.3390/ijms11093298
Received: 19 July 2010; in revised form: 30 August 2010 / Accepted: 3 September 2010 / Published: 15 September 2010
Show/Hide Abstract | Cited by 21 | PDF Full-text (251 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Biodegradability of Materials in Biomedical Applications 2011)
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Last update: 7 August 2014

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