Special Issue "Biodegradability of Materials in Biomedical Applications 2011"
Deadline for manuscript submissions: closed (31 May 2011)
Prof. Dr. Aldo R. Boccaccini
Institute of Biomaterials, Department of Materials Science and Engineering, University of Erlangen-Nuremberg, 91058 Erlangen, Germany; Visiting Professor, Department of Materials, Imperial College London, London SW7 2BP, UK
Phone: +44 207 594 6731
Fax: +44 207 594 6757
Interests: biomaterials; porous materials; scaffolds; tissue engineering; bioactive glasses; composite materials; waste recycling; carbon nanotubes; electrophoretic deposition; vascularization; bioceramics; biofabrication; bioactive coatings; drug delivery
Prof. Dr. Showan N. Nazhat
Department of Mining and Materials Engineering, McGill University, Montreal, Canada
New generation biomaterials should be able to stimulate specific cellular responses at the molecular level, moving from the concept of inertness to one of bioactivity, e.g. positive interaction at the biomaterial-tissue interface. In many cases the body needs only the temporary presence of a device or implant, in which case fully or partially biodegradable materials are better alternatives than biostable materials. The ideal biodegradable material – polymer, ceramic, metal or composite - should be biocompatible, provide adequate initial mechanical fixation, controllably degradable, and should ultimately be replaced by the regenerated tissue.
A wide range of biodegradable materials is being continuously investigated for biomedical applications, which include traditional and advanced biodegradable polymers, bioceramics and composites as well as a small group of metals and alloys based on magnesium.
Typical applications and research areas of biodegradable polymers include surgery sutures, wound dressing, antibacterial coatings, fixation devices, tissue engineering scaffolds as well as drug and cell delivery platforms. Current research focuses also on the development of biodegradable composites combining synthetic or natural biodegradable polymers and bioactive inorganic fillers, e.g. bioactive glasses and calcium phosphate ceramics, which mimic the structural characteristics of the natural extracellular matrix. Magnesium alloys are promising candidates for several structural biomedical applications due to their degradation ability combined with appropriate mechanical properties as well as good biocompatibility and are being proposed as cardiovascular stents, bone fixation devices and porous bone repair materials.
The present combined special issue in IJMS/Materials will include papers authored by researchers around the world reporting on cutting-edge results in the broad field of biodegradable materials for biomedical applications.
Prof. S. N. Nazhat
Prof. A. R. Boccaccini
Related Special Issue
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed Open Access monthly journal published by MDPI.
- biodegradable polymers
- magnesium alloys
- bioactive glasses
- calcium phosphates
- tissue engineering
- drug delivery
- wound dressing
- degradable stents
Review: Materials for Pharmaceutical Dosage Forms: Molecular Pharmaceutics and Controlled Release Drug Delivery Aspects
Int. J. Mol. Sci. 2010, 11(9), 3298-3322; doi:10.3390/ijms11093298
Received: 19 July 2010; in revised form: 30 August 2010 / Accepted: 3 September 2010 / Published: 15 September 2010| Download PDF Full-text (251 KB) | Download XML Full-text
Article: Screening and Evaluation of Polyhydroxybutyrate-Producing Strains from Indigenous Isolate Cupriavidus taiwanensis Strains
Int. J. Mol. Sci. 2011, 12(1), 252-265; doi:10.3390/ijms12010252
Received: 28 November 2010; in revised form: 26 December 2010 / Accepted: 1 January 2011 / Published: 5 January 2011| Download PDF Full-text (436 KB) | Download XML Full-text
Article: Characterization and Degradation Behavior of Agar–Carbomer Based Hydrogels for Drug Delivery Applications: Solute Effect
Int. J. Mol. Sci. 2011, 12(6), 3394-3408; doi:10.3390/ijms12063394
Received: 13 April 2011; in revised form: 18 May 2011 / Accepted: 19 May 2011 / Published: 25 May 2011| Download PDF Full-text (659 KB) | Download XML Full-text
Article: Structural Characterization of Poly-L-lactic Acid (PLLA) and Poly(glycolic acid)(PGA) Oligomers
Int. J. Mol. Sci. 2011, 12(6), 3857-3870; doi:10.3390/ijms12063857
Received: 5 May 2011; in revised form: 30 May 2011 / Accepted: 3 June 2011 / Published: 10 June 2011| Download PDF Full-text (597 KB) | Download XML Full-text
Int. J. Mol. Sci. 2011, 12(7), 4250-4270; doi:10.3390/ijms12074250
Received: 14 April 2011; in revised form: 15 June 2011 / Accepted: 19 June 2011 / Published: 29 June 2011| Download PDF Full-text (827 KB) | Download XML Full-text
Int. J. Mol. Sci. 2011, 12(7), 4294-4314; doi:10.3390/ijms12074294
Received: 23 May 2011; in revised form: 27 June 2011 / Accepted: 27 June 2011 / Published: 4 July 2011| Download PDF Full-text (862 KB) | Download XML Full-text
Article: Crystallization Study and Comparative in Vitro–in Vivo Hydrolysis of PLA Reinforcement Ligament
Int. J. Mol. Sci. 2011, 12(10), 6597-6618; doi:10.3390/ijms12106597
Received: 27 June 2011; in revised form: 24 September 2011 / Accepted: 28 September 2011 / Published: 10 October 2011| Download PDF Full-text (1309 KB) | Download XML Full-text
Last update: 26 September 2012