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Int. J. Mol. Sci. 2010, 11(9), 3298-3322; doi:10.3390/ijms11093298
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Materials for Pharmaceutical Dosage Forms: Molecular Pharmaceutics and Controlled Release Drug Delivery Aspects

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,
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Division of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, Lexington, KY 40536, USA
* Author to whom correspondence should be addressed.
Received: 19 July 2010 / Revised: 30 August 2010 / Accepted: 3 September 2010 / Published: 15 September 2010
(This article belongs to the Special Issue Biodegradability of Materials in Biomedical Applications 2011)
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Abstract

Controlled release delivery is available for many routes of administration and offers many advantages (as microparticles and nanoparticles) over immediate release delivery. These advantages include reduced dosing frequency, better therapeutic control, fewer side effects, and, consequently, these dosage forms are well accepted by patients. Advances in polymer material science, particle engineering design, manufacture, and nanotechnology have led the way to the introduction of several marketed controlled release products and several more are in pre-clinical and clinical development.
Keywords: polymers; copolymers; biomaterials; biodegradable; microparticle; nanoparticle; pharmaceutical dosage forms; particle engineering design; manufacture polymers; copolymers; biomaterials; biodegradable; microparticle; nanoparticle; pharmaceutical dosage forms; particle engineering design; manufacture
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Mansour, H.M.; Sohn, M.; Al-Ghananeem, A.; DeLuca, P.P. Materials for Pharmaceutical Dosage Forms: Molecular Pharmaceutics and Controlled Release Drug Delivery Aspects. Int. J. Mol. Sci. 2010, 11, 3298-3322.

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