Special Issue "DNA Replication"
A special issue of Genes (ISSN 2073-4425).
Deadline for manuscript submissions: closed (31 March 2015)
Prof. Dr. Peter Frank (Website)
Department of Medicine I / Institute of Cancer Research, Medical University of Vienna, Borschkegasse 8a, A-1090 Wien, Austria
Phone: +43 1 40160 57529
Fax: +43 1 40160 957500
Interests: enzymology of DNA replication and repair; RNA metabolism; molecular evolution of nucleases
Replication of DNA, even of the simplest one, is a very sophisticated process, depending on a complex enzymatic machinery being evolved over more than a billion of years. The proper action of replication is a prerequisite to maintain the genome integrity of all living organisms and together with other mechanisms it enables the evolution of life. On the one hand the universality of basic principles of duplication, derived from data obtained from the prokaryote kingdom of life, is an undisputed fact in our times. On the other hand the coordination of replication of eukaryotic genomes and the interaction between duplication and the cell division cycle is still a matter of intense research and debate. This special issue intends to demonstrate new developments and concepts in the general field of DNA replication and related topics, e.g. DNA repair. Research or review articles on any topic within the field will be considered. We are looking forward to your contributions.
Prof. Dr. Peter Frank
- eukaryotic DNA replication
- replication fork dynamics
- Okazaki fragments
- DNA polymerases