Special Issue "Heat Shock Proteins in Cancer: Chaperones of Tumorigenesis"
A special issue of Cancers (ISSN 2072-6694).
Deadline for manuscript submissions: closed (30 November 2013)
Prof. Dr. Michael Y. Sherman (Website)
Department of Biochemistry, Boston University School of Medicine, 72 East Concord Street K-323, Boston, MA 02118, USA
Interests: heat shock proteins; hsf1; senescence; breast cancer
Dr. Stuart K. Calderwood (Website)
Department of Radiation Oncology, Division of Molecular and Cellular Biology, Beth Israel Deaconess medical School, Harvard Medical School, Boston, MA 2215, USA
Interests: heat shock protein; molecular chaperone; HSF1; apoptosis; senescence; tumor growth; invasion; metastasis; angiogenesis; immunogenicity; ras; p53
Population studies and laboratory data with cells and model organisms indicate that various heat shock proteins play an important role in the genesis and progression of many cancer types. These works led to development of inhibitors of heat shock proteins, some of which have been tested in clinical trials. Since recently we have started understanding the mechanistic aspects of the role of heat shock proteins in cancer, which hopefully will teach us how to rationally combine the inhibitors with other anti-cancer drugs and what types of cancer can be treated with these inhibitors. This issue of Cancers, "Heat shock proteins in cancer: chaperones of tumorigenesis" seeks articles which will shed new light on this topic.
Prof. Dr. Michael Y. Sherman
Dr. Stuart K. Calderwood
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed Open Access monthly journal published by MDPI.
- heat shock proteins
- cancer initiation
- oncogene-induced senescence
- cancer progression