Special Issue "Heat Shock Proteins in Cancer: Chaperones of Tumorigenesis"


A special issue of Cancers (ISSN 2072-6694).

Deadline for manuscript submissions: closed (30 November 2013)

Special Issue Editors

Guest Editor
Prof. Dr. Michael Y. Sherman
Department of Biochemistry, Boston University School of Medicine, 72 East Concord Street K-323, Boston, MA 02118, USA
Website: http://www.bumc.bu.edu/biochemistry/people/faculty/michael-y-sherman/
E-Mail: sherma1@bu.edu
Phone: +1-617-638-5971
Fax: +1-617-638-5339
Interests: heat shock proteins; hsf1; senescence; breast cancer

Guest Editor
Dr. Stuart K. Calderwood
Department of Radiation Oncology, Division of Molecular and Cellular Biology, Beth Israel Deaconess medical School, Harvard Medical School, Boston, MA 2215, USA
Website: http://connects.catalyst.harvard.edu/Profiles/display/Person/53611
E-Mail: scalderw@bidmc.harvard.edu
Interests: heat shock protein; molecular chaperone; HSF1; apoptosis; senescence; tumor growth; invasion; metastasis; angiogenesis; immunogenicity; ras; p53

Special Issue Information

Dear Colleagues,

Population studies and laboratory data with cells and model organisms indicate that various heat shock proteins play an important role in the genesis and progression of many cancer types. These works led to development of inhibitors of heat shock proteins, some of which have been tested in clinical trials. Since recently we have started understanding the mechanistic aspects of the role of heat shock proteins in cancer, which hopefully will teach us how to rationally combine the inhibitors with other anti-cancer drugs and what types of cancer can be treated with these inhibitors. This issue of Cancers, "Heat shock proteins in cancer: chaperones of tumorigenesis" seeks articles which will shed new light on this topic.

Prof. Dr. Michael Y. Sherman
Dr. Stuart K. Calderwood
Guest Editors


Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed Open Access quarterly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 800 CHF (Swiss Francs).


  • chaperones
  • heat shock proteins
  • cancer initiation
  • oncogene-induced senescence
  • cancer progression
  • metastasis
  • angiogenesis

Published Papers (6 papers)

by , , ,  and
Cancers 2014, 6(3), 1382-1393; doi:10.3390/cancers6031382
Received: 16 January 2014; in revised form: 25 April 2014 / Accepted: 16 June 2014 / Published: 27 June 2014
Show/Hide Abstract | PDF Full-text (1177 KB) | HTML Full-text | XML Full-text

by ,  and
Cancers 2014, 6(2), 1065-1097; doi:10.3390/cancers6021065
Received: 13 March 2014; in revised form: 16 April 2014 / Accepted: 24 April 2014 / Published: 6 May 2014
Show/Hide Abstract | PDF Full-text (1100 KB) | HTML Full-text | XML Full-text

by , , ,  and
Cancers 2014, 6(2), 1031-1046; doi:10.3390/cancers6021031
Received: 12 December 2013; in revised form: 12 March 2014 / Accepted: 8 April 2014 / Published: 30 April 2014
Show/Hide Abstract | PDF Full-text (873 KB) | HTML Full-text | XML Full-text

by , , ,  and
Cancers 2014, 6(2), 998-1019; doi:10.3390/cancers6020998
Received: 6 December 2013; in revised form: 15 March 2014 / Accepted: 3 April 2014 / Published: 23 April 2014
Show/Hide Abstract | PDF Full-text (1072 KB) | HTML Full-text | XML Full-text | Supplementary Files

by  and
Cancers 2014, 6(1), 333-365; doi:10.3390/cancers6010333
Received: 11 November 2013; in revised form: 3 January 2014 / Accepted: 17 January 2014 / Published: 7 February 2014
Show/Hide Abstract | Cited by 1 | PDF Full-text (1086 KB) | HTML Full-text | XML Full-text
abstract graphic

by , , , , ,  and
Cancers 2014, 6(1), 42-66; doi:10.3390/cancers6010042
Received: 7 November 2013; in revised form: 5 December 2013 / Accepted: 11 December 2013 / Published: 20 December 2013
Show/Hide Abstract | Cited by 2 | PDF Full-text (968 KB) | HTML Full-text | XML Full-text | Supplementary Files

Last update: 23 July 2013

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