Special Issue "Calcium Binding Proteins: Structure, Properties, Functions"

A special issue of Biomolecules (ISSN 2218-273X).

Deadline for manuscript submissions: 30 June 2018

Special Issue Editors

Guest Editor
Prof. Dr. Eugene Permyakov

Director of the Institute for Biological Instrumentation of the Russian Academy of Sciences, 7 Institutskaya str., Pushchino, Moscow region 142290, Russia
Website | E-Mail
Phone: 7 495 624 57 49
Fax: +7 4967 33 05 22
Interests: metal binding proteins; calcium binding proteins; intrinsically disordered proteins; intrinsic protein fluorescence; parvalbumin; α-lactalbumin; S100 proteins; recoverin
Guest Editor
Assoc. Prof. Dr. Vladimir N. Uversky

Molecular Medicine, University of South Florida, Tampa, USA
Website | E-Mail
Interests: intrinsically disordered proteins; protein folding; protein misfolding; partially folded proteins; protein aggregation; protein structure; protein function; protein biophysics; protein bioinformatics; conformational diseases; protein–ligand interactions; protein–protein interactions

Special Issue Information

Dear Colleagues, 

Calcium regulates all important aspects of cell activity, beginning with fertilization and ending with the apoptotic suicide at the end of the life cycle. Calcium binding proteins play important roles in practically all biological processes. Now we know several large families of calcium binding proteins and three-dimensional structures of their main representatives are well known. Nevertheless, each year brings us many new structures. Analysis of these structures allows revealing general principles of their design, which can be used in protein engineering. Most calcium binding proteins play regulatory roles activating or deactivating various biological systems. Calcium-binding proteins of cytosol and membrane calcium-binding proteins directed to cytosol are called calcium modulated proteins as they take part in generation of calcium gradient across cells and/or transfer external impulse information. At the same time, there exist calcium binding proteins, which modulate calcium flows inside cells. In spite of the knowledge of three-dimensional structures of many calcium binding proteins, the exact physiological function of many of them is still unknown or known only hypothetically.

It is useful from time to time to collect our new knowledge on calcium binding proteins in several good reviews to draw some generalizations for further success of our future academic studies and applied developments. This is the main goal of the present Special Issue of Biomolecules.

Prof. Dr. Eugene Permyakov
Dr. Vladimir N. Uversky
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomolecules is an international peer-reviewed open access quarterly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 650 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • calcium binding proteins
  • metal binding proteins
  • structure
  • function
  • regulation

Published Papers

This special issue is now open for submission.
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