Drug-Loaded Nanofibers: Controlled and Sustained Release
A special issue of Pharmaceutics (ISSN 1999-4923).
Deadline for manuscript submissions: closed (6 December 2019) | Viewed by 4495
Special Issue Editor
Interests: bioabsorbable medical devices; drug delivery; tissue engineering; nanofibers; core-shell microspheres
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Nanofibers from a rich variety of materials including polymers, composites, and ceramics can be easily prepared using simple methods such as electrospinning. Drug-loaded nanofibers have attracted a great deal of attention over the past two decades due to their unique characteristics, and are exploited as promising materials for a wide range of drug delivery applications. Furthermore, drug-loaded nanofibers provide various advantages including: 1) due to the high surface area to volume ratio, polymer nanofibers provide a useful pathway for the delivery of water insoluble drugs; 2) the drug release profile can be easily fine-tailored by modulation not only of the composition of the nanofiber mats but also the morphology of nanofibers, the process and the micro-structure; 3) there is a lot of flexibility in the use of nanofibers in designing various dosage forms to achieve the maximum bioavailability of a drug moiety for different drug delivery routes; 4) nanofibers often possess a higher drug encapsulation efficiency than other nanotechnologies; 5) drug-loaded nanofibers not only have one dimension at the microscopic scale but another dimension in the macroscopic form, thus offering the advantages of conventional solid dosage forms such as easy processing, good drug stability, and ease of packaging and shipping.
This Special Issue of Pharmaceutics will attempt to cover the recent advancements in the fabrications and applications of these drug-loaded nanofibers.
Prof. Dr. Shih-Jung (Sean) Liu
Guest Editor
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Keywords
- nanofibers
- drug delivery
- release characteristics
- fabrication
- applications
