Special Issue "Alternatives to Antibiotics: Current Strategies and Future Prospects"


A special issue of Pathogens (ISSN 2076-0817).

Deadline for manuscript submissions: closed (31 October 2014)

Special Issue Editor

Guest Editor
Dr. Guolong Zhang

Department of Animal Science, Oklahoma State University, Stillwater, OK 74078, USA
Website: http://ansi.okstate.edu/the-department/people/faculty-pages/zhang
Fax: +1 405-744-7390
Interests: innate immunity; host defense peptides; antibiotic alternatives

Special Issue Information

Dear Colleagues,

Subtherapeutic use of antibiotics in animal agriculture poses a serious threat to public health by increasing the risk of disseminating antibiotic-resistant pathogens. The European Union has banned the use of antibiotics as growth promoters. The U.S. Food and Drug Administration is implementing a new policy to phase out the application of medically important antibiotics to healthy animals by December 2016. Alternatives to antibiotics are, therefore, urgently needed to ensure animal health and productivity and food safety and security. Although a long list of compounds are currently available on the antibiotic alternatives market, very few can match the efficacy of antibiotics in growth promotion and disease resistance. This Special Issue will provide an update on our search for more effective antibiotic alternatives. More importantly, some of the promising strategies that are being developed will be highlighted. This special issue will also serve as a platform for leading researchers to discuss the future directions of our pursuit for alternatives to antibiotics.

Dr. Guolong Zhang
Guest Editor


Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pathogens is an international peer-reviewed Open Access quarterly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 600 CHF (Swiss Francs). English correction and/or formatting fees of 250 CHF (Swiss Francs) will be charged in certain cases for those articles accepted for publication that require extensive additional formatting and/or English corrections.


  • antimicrobial resistance
  • antibiotic growth promoters
  • antibiotic alternatives
  • host defense peptides
  • antimicrobial peptides
  • immunomodulators
  • probiotics
  • bacteriocins
  • bacteriophages
  • essential oils
  • phytochemicals

Published Papers (5 papers)

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Displaying article 1-5
p. 137-156
by , ,  and
Pathogens 2015, 4(1), 137-156; doi:10.3390/pathogens4010137
Received: 3 February 2015 / Revised: 18 March 2015 / Accepted: 19 March 2015 / Published: 23 March 2015
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p. 34-45
by , ,  and
Pathogens 2015, 4(1), 34-45; doi:10.3390/pathogens4010034
Received: 6 November 2014 / Revised: 22 December 2014 / Accepted: 22 January 2015 / Published: 27 January 2015
Show/Hide Abstract | Cited by 4 | PDF Full-text (216 KB) | HTML Full-text | XML Full-text
p. 1-19
by  and
Pathogens 2015, 4(1), 1-19; doi:10.3390/pathogens4010001
Received: 25 October 2014 / Accepted: 24 December 2014 / Published: 29 December 2014
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p. 947-956
by , ,  and
Pathogens 2014, 3(4), 947-956; doi:10.3390/pathogens3040947
Received: 3 November 2014 / Revised: 11 December 2014 / Accepted: 12 December 2014 / Published: 17 December 2014
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p. 667-679
by , , , ,  and
Pathogens 2014, 3(3), 667-679; doi:10.3390/pathogens3030667
Received: 19 June 2014 / Revised: 11 July 2014 / Accepted: 29 July 2014 / Published: 6 August 2014
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Last update: 8 April 2014

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