Special Issue "Diet and Cancer Prevention"
A special issue of Nutrients (ISSN 2072-6643).
Deadline for manuscript submissions: closed (31 July 2011)
Dr. Cindy D. Davis (Website)
Director of Grants and Extramural Activities, Office of Dietary Supplements, National Institutes of Health, 6100 Executive Blvd., Room 3B01, MSC 7517, Bethesda, MD 20892-7517, USA
Fax: +301 4801845
Interests: diet and cancer prevention; selenium; vitamin D
Malignant cells are characterized by numerous alterations in multiple signaling pathways that promote proliferation, inhibit apoptosis, promote angiogenesis in the case of solid tumors, and enable cancer cells to invade and migrate through tissues. Bioactive dietary components have been shown to modify all of the major signaling pathways which are deregulated in cancer. Estimates suggest that 30-70% of all cancer cases might be preventable by diet, depending on the dietary components and the specific type of cancer. A better understanding of the bioactive components present in food, the mechanism(s) of action of these dietary components towards cancer prevention, the critical intake of dietary components, duration and when they should be provided to optimize the desired physiological response is needed. The purpose of this special issue is to focus on the role of bioactive food components in cancer prevention.
Dr. Cindy D. Davis
- cancer prevention
- molecular targets
- cell proliferation