Special Issue "Photodynamic Therapy"
Deadline for manuscript submissions: closed (31 October 2016)
Prof. Dr. Norbert Lange
Photodynamic therapy (PDT) is based on the topical or systemic administration of a photosensitizer preferentially accumulated in a diseased target tissue. Irradiation of the diseased area triggers the production of toxic reactive oxygen species, subsequently leading to cell death. Furthermore, the photosensitizer’s ability to localize in diseases tissue can be used for the improved detection of disease because most of these molecules are intrinsically fluorescent. Most photosensitizers are based on porphyrins and phthalocyanines, though other chemical skeletons have been considered. Since its first description at the beginning of the 20th century, intensive research in PDT has provided profound insight into improved treatment modalities. Currently, PDT is developing intensively into other fields including bacterial inactivation and photochemical internalization.
Although not completely integrated into daily clinical practice in most areas, nowadays PDT represents of valid piece in today’s clinician’s toolbox for the curative and palliative treatment of several diseases, including head and neck cancer, age related macular degeneration, esophageal cancer, and skin cancer to name a few.
This special issue on photodynamic therapy is dedicated to the newest information in this research field. It should reflect a roundtable of the most proficient researches in photodynamic therapy. We expect an intensive debate and the latest findings on improved photosensitizers, innovative drug delivery strategies in PDT, and current and potential applications in clinical practice.
Prof. Dr. Norbert Lange
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.