Special Issue "Olefin Metathesis and Its Application"


A special issue of Molecules (ISSN 1420-3049).

Deadline for manuscript submissions: closed (31 March 2012)

Special Issue Editor

Guest Editor
Dr. Anna G. Wenzel
Joint Science Department, Claremont McKenna, Pitzer and Scripps Colleges, Claremont, California 91711, USA
E-Mail: awenzel@jsd.claremont.edu
Interests: asymmetric catalysis; organometallic cemistry; organic synthesis

Special Issue Information

Dear Colleagues,

The reliable and efficient generation of carbon-carbon bonds underpins the foundation of chemical synthesis. Of these, olefin metathesis has risen to the forefront of the methods utilized for the preparation of alkenes. Catalyst developments in the past 25 years have dramatically increased the accessibility of this reaction for general use, with many catalysts now being commercially available. In addition, significant progress has been made in understanding the catalyst and substrate structural features, their interactions, and experimental conditions crucial to reaction selectivity. This has led to numerous applications of olefin metathesis in both academia and industry. In particular, cross-metathesis, ring-closing metathesis, enyne metathesis, ring-rearrangement metathesis, as well as tandem processes, remain highly active areas of investigation.

Despite the progress that has been achieved, many challenges remain, principally with regard to catalyst stability and control. The issue of control manifests itself in a myriad of ways, be it regiochemical or stereochemical. For example, the issue of olefin diastereocontrol in metathesis remains a significant challenge due to the thermodynamic nature of the reaction. Additionally, the pursuit of substrate control, while maintaining high catalyst turnover numbers in the face of steric and electronic impediments, remains a significant goal of catalyst design. Fortunately, recent years have seen many elegant solutions towards progress in overcoming these hurdles.

This Special Issue on olefin metathesis will offer an attractive forum to present recent results in olefin metathesis pertaining to catalyst development, broadened substrate scope and/or stereocontrol, as well as the application of olefin metathesis to synthesis. I strongly encourage authors to submit papers for Molecules’ Special Issue on Olefin Metathesis. I believe that the topics covered will thoroughly convey the expanding potential and applicability of this versatile reaction.

Dr. Anna G. Wenzel
Guest Editor


  • olefin metathesis
  • ruthenium
  • molybdenum
  • transition metal
  • alkylidene
  • catalytic

Published Papers (6 papers)

by ,  and
Molecules 2011, 16(8), 6871-6882; doi:10.3390/molecules16086871
Received: 4 May 2011; in revised form: 8 July 2011 / Accepted: 12 July 2011 / Published: 11 August 2011
Show/Hide Abstract | Cited by 13 | PDF Full-text (443 KB)

Molecules 2011, 16(9), 7844-7863; doi:10.3390/molecules16097844
Received: 30 June 2011; in revised form: 4 August 2011 / Accepted: 5 September 2011 / Published: 13 September 2011
Show/Hide Abstract | Cited by 11 | PDF Full-text (1975 KB)

Molecules 2012, 17(3), 3348-3358; doi:10.3390/molecules17033348
Received: 28 February 2012; in revised form: 7 March 2012 / Accepted: 13 March 2012 / Published: 15 March 2012
Show/Hide Abstract | Cited by 11 | PDF Full-text (463 KB)

by ,  and
Molecules 2012, 17(5), 5177-5186; doi:10.3390/molecules17055177
Received: 1 April 2012; in revised form: 25 April 2012 / Accepted: 26 April 2012 / Published: 4 May 2012
Show/Hide Abstract | Cited by 2 | PDF Full-text (359 KB)

by , ,  and
Molecules 2012, 17(5), 5675-5689; doi:10.3390/molecules17055675
Received: 28 March 2012; in revised form: 18 April 2012 / Accepted: 23 April 2012 / Published: 11 May 2012
Show/Hide Abstract | Cited by 3 | PDF Full-text (345 KB)

by ,  and
Molecules 2012, 17(5), 6001-6010; doi:10.3390/molecules17056001
Received: 16 March 2012; in revised form: 30 April 2012 / Accepted: 3 May 2012 / Published: 18 May 2012
Show/Hide Abstract | Cited by 3 | PDF Full-text (245 KB)

Last update: 4 March 2014

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