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Molecules 2012, 17(3), 3348-3358; doi:10.3390/molecules17033348

Synthesis of Tetrasubstituted Alkenes via Metathesis

College of Pharmacy, Research Institute of Pharmaceutical Sciences, Gyeongsang National University, Jinju daero, Jinju, Gyeongnam 660-751, Korea
Received: 28 February 2012 / Revised: 7 March 2012 / Accepted: 13 March 2012 / Published: 15 March 2012
(This article belongs to the Special Issue Olefin Metathesis and Its Application)
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Fully substituted olefin generation via metathesis is presented. Catalyst development, optimization of reaction conditions and substrate screening are included. In addition, asymmetric alkene metathesis, the cross metathesis reaction for this transformation and its application in natural products will be discussed.
Keywords: tetrasubstituted alkene; metathesis; catalyst tetrasubstituted alkene; metathesis; catalyst
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Paek, S.-M. Synthesis of Tetrasubstituted Alkenes via Metathesis. Molecules 2012, 17, 3348-3358.

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