Isocyanide

Dear Colleagues,

Isocyanides are immensely valuable building-blocks used in both ionic and radical processes. These versatile synthons are well-designed for Multicomponent Reactions (MCRs), as attested by the huge success of the Ugi reaction. The development of new isocyanide-based MCRs (IMCRs), as well as the development of new cascades involving an IMCR, are of paramount importance to enlarge, even more, the molecular diversity attainable within a few synthetic steps. In addition to their interest for MCRs, isocyanides are isoelectronic with carbon monoxide and behave as non-toxic and are easily-handled analogues towards transition metals. Isocyanides have been known to be efficient metal ligands for a long time, and, since the early 1970s, a wide range of organometallic complexes have been described. Very recently, imidoylative metal-catalyzed processes have attracted intense research efforts and had a tremendous impact in heterocyclic synthesis. In this Special Issue, we intend to collect original contributions to provide a broad survey of the state-of-the-art in isocyanide chemistry. Reviews articles by experts in the field will also be welcome.

Dr. Laurence Grimaud
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• multicomponent reactions
• Ugi and Passerini reactions
• radical additions
• heterocyclic Chemistry
• organometallic complexes
• imidoylative processes
• isocyanide insertion