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Application of Ultrasound in Chemical Reaction

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Ultrasound Chemistry".

Deadline for manuscript submissions: closed (31 January 2024) | Viewed by 6091

Special Issue Editor


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Guest Editor
Department of Food Science and Technology, Ferdowsi University of Mashhad (FUM), P.O. Box 91775‐1163, Mashhad, Iran
Interests: starch; food hydrocolloids; food emulsions

Special Issue Information

Dear Colleagues,

Ultrasound has a significant impact on food, cosmetic, pharmaceutical, and chemical materials. Ultrasound-induced cavitation alters the physical and chemical characteristics of materials. Mechanical (such as cleaning, dispersion, friction, interface instability, degassing, defoaming, and others) and chemical (bond-breaking and bond-forming reactions) effects all occur during ultrasonic cavitation. Emulsification, microstructure modification, textural modification, and sonocrystallization are among the numerous applications of these waves. Due to its high efficiency, ease of use, repeatability, and controllability, ultrasound has recently become increasingly used for the fabrication and modification of new materials in addition to well-known medical applications. In order to efficiently extract the soluble constituents of living tissues, ultrasound is frequently used in the field of biochemistry to disintegrate cells. Even though numerous studies have demonstrated the ability of ultrasound to alter naturally derived materials, this method is still relatively new in the world of biological and organic materials. This Special Issue will include the most recent advancements of ultrasound techniques used for these materials, demonstrating the enormous potential that this area holds for the development of novel materials.

Dr. Arash Koocheki
Guest Editor

Manuscript Submission Information

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Keywords

  • synthesis of organic materials
  • ultrasonic-assisted extraction of material
  • modification of functional properties of food
  • ultrasonic preparation of emulsions
  • modification of polymers
  • ultrasound in biomedical applications

Published Papers (3 papers)

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Research

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16 pages, 2521 KiB  
Article
Biological Activities of Citrus aurantium Leaf Extract by Optimized Ultrasound-Assisted Extraction
by Guey-Horng Wang, Chun-Ta Huang, Hsiu-Ju Huang, Chi-Hsiang Tang and Ying-Chien Chung
Molecules 2023, 28(21), 7251; https://doi.org/10.3390/molecules28217251 - 24 Oct 2023
Viewed by 1043
Abstract
Several studies have explored the biological activities of Citrus aurantium flowers, fruits, and seeds, but the bioactivity of C. aurantium leaves, which are treated as waste, remains unclear. Thus, this study developed a pilot-scale ultrasonic-assisted extraction process using the Box–Behnken design (BBD) for [...] Read more.
Several studies have explored the biological activities of Citrus aurantium flowers, fruits, and seeds, but the bioactivity of C. aurantium leaves, which are treated as waste, remains unclear. Thus, this study developed a pilot-scale ultrasonic-assisted extraction process using the Box–Behnken design (BBD) for the optimized extraction of active compounds from C. aurantium leaves, and their antityrosinase, antioxidant, antiaging, and antimicrobial activities were evaluated. Under optimal conditions in a 150× scaleup configuration (a 30 L ultrasonic machine) of a pilot plant, the total phenolic content was 69.09 mg gallic acid equivalent/g dry weight, which was slightly lower (3.17%) than the theoretical value. The half maximal inhibitory concentration of C. aurantium leaf extract (CALE) for 2,2-diphenyl-1-picrylhydrazyl–scavenging, 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid)–scavenging, antityrosinase, anticollagenase, antielastase and anti-matrix metalloprotein-1 activities were 123.5, 58.5, 181.3, 196.4, 216.3, and 326.4 mg/L, respectively. Moreover, the minimal inhibitory concentrations for bacteria and fungi were 150–350 and 500 mg/L, respectively. In total, 17 active compounds were detected in CALE—with linalool, linalyl acetate, limonene, and α-terpineol having the highest concentrations. Finally, the overall transdermal absorption and permeation efficiency of CALE was 95.9%. In conclusion, our CALE demonstrated potential whitening, antioxidant, antiaging, and antimicrobial activities; it was also nontoxic and easily absorbed into the skin as well as inexpensive to produce. Therefore, it has potential applications in various industries. Full article
(This article belongs to the Special Issue Application of Ultrasound in Chemical Reaction)
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17 pages, 15878 KiB  
Article
Evaluation of the Effect of Ultrasonic Pretreatment on the Drying Kinetics and Quality Characteristics of Codonopsis pilosula Slices Based on the Grey Correlation Method
by Tongxun Wang, Xinyu Ying, Qian Zhang, Yanrui Xu, Chunhui Jiang, Jianwei Shang, Zepeng Zang, Fangxin Wan and Xiaopeng Huang
Molecules 2023, 28(14), 5596; https://doi.org/10.3390/molecules28145596 - 24 Jul 2023
Cited by 5 | Viewed by 1151
Abstract
Ultrasonic (US) maltreatment was performed before the vacuum far-infrared drying (VFID) of Codonopsis pilosula (CP) slices to investigate the effects of different US parameters on the drying characteristics and nutrients of CP slices. The grey correlation method with relative correlation degree (r [...] Read more.
Ultrasonic (US) maltreatment was performed before the vacuum far-infrared drying (VFID) of Codonopsis pilosula (CP) slices to investigate the effects of different US parameters on the drying characteristics and nutrients of CP slices. The grey correlation method with relative correlation degree (ri) as the evaluation measure was used to construct a model for the evaluation of the pretreatment quality of CP and to determine the optimal pretreatment conditions. The results showed that with the increase in US frequency and power, the drying rate increased. Under the conditions of US power of 180 W, frequency of 60 kHz and a pre-treatment time of 30 min, the drying time reduced by 28.6%. The contents of polysaccharide and syringin in dried CP slices pretreated by US increased by 14.7% and 62.0%, respectively, compared to the non-pre-treated samples, while the total flavonoid content decreased by 10.0%. In terms of colour, pretreatment had a certain protective effect on the red colour of dried products. The highest relative correlation (0.574) and the best overall quality of performance were observed at 180 W, 60 kHz and 30 min. Overall, US technology is suitable for the pretreatment processing of CP, which is of great significance to the drying of CP. Full article
(This article belongs to the Special Issue Application of Ultrasound in Chemical Reaction)
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Review

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31 pages, 9082 KiB  
Review
Synthesis of Imidazole-Based Molecules under Ultrasonic Irradiation Approaches
by Xian-Long Yu, Yu-Han Fan, Xu-Nan Zheng, Jing-Fei Gao, Li-Geng Zhuang, Yang-Ling Yu, Jing-Hui Xi and Da-Wei Zhang
Molecules 2023, 28(12), 4845; https://doi.org/10.3390/molecules28124845 - 19 Jun 2023
Cited by 5 | Viewed by 3448
Abstract
Imidazole-based compounds are a series of heterocyclic compounds that exhibit a wide range of biological and pharmaceutical activities. However, those extant syntheses using conventional protocols can be time-costly, require harsh conditions, and result in low yields. As a novel and green technique, sonochemistry [...] Read more.
Imidazole-based compounds are a series of heterocyclic compounds that exhibit a wide range of biological and pharmaceutical activities. However, those extant syntheses using conventional protocols can be time-costly, require harsh conditions, and result in low yields. As a novel and green technique, sonochemistry has emerged as a promising method for organic synthesis with several advantages over conventional methods, including enhancing reaction rates, improving yields, and reducing the use of hazardous solvents. Contemporarily, a growing body of ultrasound-assisted reactions have been applied in the preparation of imidazole derivatives, which demonstrated greater benefits and provided a new strategy. Herein, we introduce the brief history of sonochemistry and focus on the discussion of the multifarious approaches for the synthesis of imidazole-based compounds under ultrasonic irradiation and its advantages in comparison with conventional protocols, including typical name-reactions and various sorts of catalysts in those reactions. Full article
(This article belongs to the Special Issue Application of Ultrasound in Chemical Reaction)
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