Special Issue "New and Old Technologies for Generation of Microarrays"


A special issue of Microarrays (ISSN 2076-3905).

Deadline for manuscript submissions: 31 January 2015

Special Issue Editor

Guest Editor
Dr. Günter Roth
Albert-Ludwigs-University Freiburg, Center for Biological Systems Analysis (ZBSA), Habsburgerstrasse 49, D-79104 Freiburg, Germany
Website: http://www.imtek.de/laboratories/mems-applications/staff/personal-websites/roth
E-Mail: guenter.roth@zbsa.uni-freiburg.de
Interests: microarrays; label-free detection and binding kinetic determination; mobile applications; copying NGS chips into microarrays

Special Issue Information

Dear Colleagues,

Microarrays have been the first method of choice for highly parallel DNA and RNA analysis as well as in molecular interaction studies. Even though Next Generation Sequencing (NGS) is believed to soon be able to count each RNA copy in a single cell; microarrays are still irreplaceable, especially in the field of proteins, antibodies and small molecules. Nevertheless the increasing demand in throughput, molecular purity, robustness and effective production leads to improvement of the old techniques of microarray generation and to innovative ideas of ‘making’ microarrays in completely new ways. Therefore ‘the simple act’ of Microarray Generation is the focus of this Special Issue “Microarray Generation—Old Paths and New Ways”. It will highlight the old and successful paths such as light-synthesis, spot-synthesis and outline future improvements to the reader, but also offer a glimpse into what is emerging at the moment and what is yet to come, i.e., what new possibilities may become available in the not too distant future. You are invited to present new ways of microarray generation, but also to provide proof that the old ‘paths’ still bear potential for vast improvements.

With best regards,

Dr. Günter Roth
Guest Editor


Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Microarrays is an international peer-reviewed Open Access quarterly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. For the first couple of issues the Article Processing Charge (APC) will be waived for well-prepared manuscripts. English correction and/or formatting fees of 250 CHF (Swiss Francs) will be charged in certain cases for those articles accepted for publication that require extensive additional formatting and/or English corrections.

Special Issue Flyer

Please download the special issue flyer here.


  • microarray generation
  • DNA synthesis
  • RNA synthesis
  • protein synthesis
  • DAPA
  • PISA
  • microarray copying
  • light synthesis
  • spot synthesis
  • microarray printing

Published Papers (1 paper)

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p. 245-262
by , , , , , , , , , , , , ,  and
Microarrays 2014, 3(4), 245-262; doi:10.3390/microarrays3040245
Received: 4 August 2014; in revised form: 15 October 2014 / Accepted: 16 October 2014 / Published: 28 October 2014
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Planned Papers

The below list represents only planned manuscripts. Some of these manuscripts have not been received by the Editorial Office yet. Papers submitted to MDPI journals are subject to peer-review.

Title: Label Detection and Label-free Detection for Protein Microarrays
Amir Syahir1, Kenji Usui2,*, Kin-ya Tomizaki3, Kotaro Kajikawa4, Hisakazu Mihara5,*
1Department of Biochemistry, Faculty of Biotechnology and Biomolecular Science, Universiti Putra Malaysia, Serdang 43400, Malaysia.
Faculty of Frontiers of Innovative Research in Science and Technology (FIRST), Konan University, Kobe, 650-0047, Japan.
Department of Materials Chemistry, Ryukoku University, Seta, Otsu 520-2194, Japan.
Department of Electronics and Applied Physics Interdisciplinary Graduate School of Science and Engineering, Tokyo Institute of Technology, Yokohama 226-8502, Japan.
Department of Bioengineering, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, Yokohama 226-8501, Japan. E-Mails: kusui@center.konan-u.ac.jp
Microarray has gone through many innovative developments in the recent decades. In this review, we focus on the development of protein detection methods embedded in the technology. Early works on microarray have utilized many useful chromophores and versatile biochemical techniques dominated the high-throughput illumination. Recently the realization of label-free techniques integrating into the microarray has been greatly advanced by the combination of knowledge in material sciences, computational design, and nanofabrication. These rapidly growing new techniques are aiming at providing data without the intervention of any label molecules. Here we present a brief overview of this remarkable innovation from both perspectives of label and label-free techniques in transducing nano-biological events.

Title: Aptamer Microarrays: Interesting Alternative for the Detection of Various Targets
Author: Frank Stahl
Affiliation: Leibniz Universität Hannover, Institut für Technische Chemie, Callinstr. 5, 30167 Hannover, Germany; E-Mails: stahl@iftc.uni-hannover.de

Last update: 19 December 2014

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