Special Issue "Biodegradable Metals"

A special issue of Metals (ISSN 2075-4701).

Deadline for manuscript submissions: 31 January 2018

Special Issue Editor

Guest Editor
Prof. Dr. Eli Aghion

Department of Materials Engineering, Ben-Gurion University of the Negev, Beer Sheva, Israel
Website | E-Mail

Special Issue Information

Dear Colleagues,

The interest in biocompatible and biodegradable metals, such as magnesium, is mainly related to their potential use as structural material for orthopedic and cardiovascular applications where a temporary medical device is required. However, in the case of magnesium, in vivo experiments have clearly shown that the corrosion degradation rate of magnesium and its alloys is too high and, hence, results in producing gas cavities that can promote the danger of gas embolism, tissue separation, and premature loss of mechanical integrity. The aim of this Special Issue on Biodegradable Metals is to explore and introduce innovative strategies to overcome the current limitations of magnesium. Papers relating to other potential biodegradable metals, such as Iron and Zinc, are also welcome.

Prof. Dr. Eli Aghion
Guest Editor

Manuscript Submission Information

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Keywords

  • Magnesium
  • Iron
  • Zinc
  • Biomaterials
  • Implants
  • Biocompatibility
  • Biodegradable
  • Bioabsorble
  • Biocorrosion

Published Papers (3 papers)

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Research

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Open AccessArticle Preparation and Characterization of Zinc Materials Prepared by Powder Metallurgy
Metals 2017, 7(10), 396; doi:10.3390/met7100396
Received: 30 August 2017 / Revised: 18 September 2017 / Accepted: 22 September 2017 / Published: 27 September 2017
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Abstract
The use of zinc-based materials as biodegradable materials for medical purposes is offered as a possible alternative to corrosion-less resistant magnesium-based materials. Zinc powders with two different particle sizes (7.5 µm and 150 µm) were processed by the methods of powder metallurgy: cold
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The use of zinc-based materials as biodegradable materials for medical purposes is offered as a possible alternative to corrosion-less resistant magnesium-based materials. Zinc powders with two different particle sizes (7.5 µm and 150 µm) were processed by the methods of powder metallurgy: cold pressing, cold pressing followed by sintering and hot pressing. The microstructure of prepared materials was evaluated in terms of light optical microscopy, and the mechanical properties were analyzed with Vickers microhardness testing and three-point bend testing. Fractographic analysis of broken samples was performed with scanning electron microscopy. Particle size was shown to have a significant effect on compacts mechanical properties. The deformability of 7.5 µm particle size powder was improved by increased temperature during the processing, while in the case of larger powder, no significant influence of temperature was observed. Bending properties of prepared materials were positively influenced by elevated temperature during processing and correspond to the increasing compacting pressures. Better properties were achieved for pure zinc prepared from 150 µm particle size powder compared to materials prepared from 7.5 µm particle size powder. Full article
(This article belongs to the Special Issue Biodegradable Metals)
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Open AccessFeature PaperArticle Investigation on Mechanical Behavior of Biodegradable Iron Foams under Different Compression Test Conditions
Metals 2017, 7(6), 202; doi:10.3390/met7060202
Received: 13 April 2017 / Revised: 25 May 2017 / Accepted: 30 May 2017 / Published: 2 June 2017
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Abstract
Biodegradable metal foams have been studied as potential materials for bone scaffolds. Their mechanical properties largely depend on the relative density and micro-structural geometry. In this work, mechanical behavior of iron foams with different cell sizes was investigated under various compression tests in
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Biodegradable metal foams have been studied as potential materials for bone scaffolds. Their mechanical properties largely depend on the relative density and micro-structural geometry. In this work, mechanical behavior of iron foams with different cell sizes was investigated under various compression tests in dry and wet conditions and after subjected to degradation in Hanks’ solution. Statistical analysis was performed using hypothesis and non-parametric tests. The deformation behavior of the foams under compression was also evaluated. Results show that the mechanical properties of the foams under dry compression tests had a “V-type” variation, which is explained as a function of different geometrical properties by using a simple tabular method. The wet environment did not change the compression behavior of the iron foams significantly while degradation decreased the elastic modulus, yield and compression strengths and the energy absorbability of the specimens. The deformation of open cell iron foams under compression is viewed as a complex phenomenon which could be the product of multiple mechanism such as bending, buckling and torsion. Full article
(This article belongs to the Special Issue Biodegradable Metals)
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Review

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Open AccessReview The Prospects of Zinc as a Structural Material for Biodegradable Implants—A Review Paper
Metals 2017, 7(10), 402; doi:10.3390/met7100402
Received: 31 August 2017 / Revised: 21 September 2017 / Accepted: 22 September 2017 / Published: 1 October 2017
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Abstract
In the last decade, iron and magnesium, both pure and alloyed, have been extensively studied as potential biodegradable metals for medical applications. However, broad experience with these material systems has uncovered critical limitations in terms of their suitability for clinical applications. Recently, zinc
[...] Read more.
In the last decade, iron and magnesium, both pure and alloyed, have been extensively studied as potential biodegradable metals for medical applications. However, broad experience with these material systems has uncovered critical limitations in terms of their suitability for clinical applications. Recently, zinc and zinc-based alloys have been proposed as new additions to the list of degradable metals and as promising alternatives to magnesium and iron. The main byproduct of zinc metal corrosion, Zn2+, is highly regulated within physiological systems and plays a critical role in numerous fundamental cellular processes. Zn2+ released from an implant may suppress harmful smooth muscle cells and restenosis in arteries, while stimulating beneficial osteogenesis in bone. An important limitation of pure zinc as a potential biodegradable structural support, however, lies in its low strength (σUTS ~ 30 MPa) and plasticity (ε < 0.25%) that are insufficient for most medical device applications. Developing high strength and ductility zinc with sufficient hardness, while retaining its biocompatibility, is one of the main goals of metallurgical engineering. This paper will review and compare the biocompatibility, corrosion behavior and mechanical properties of pure zinc, as well as currently researched zinc alloys. Full article
(This article belongs to the Special Issue Biodegradable Metals)
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