Special Issue "Environmental Metabolomics"
A special issue of Metabolites (ISSN 2218-1989).
Deadline for manuscript submissions: closed (31 August 2017)
Dr. Manuel Liebeke
Max Planck Institute for Marine Microbiology, Department of Symbiosis, Celsius Strasse 1, 28359 Bremen, Germany
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Interests: mass spectral imaging, metabolic profiling, symbiosis, microbial metabolomics, marine and terrestrial invertebrate metabolism, host-pathogen interactions, mass spectrometry, gas chromatography, sample preparation for metabolomics
With emerging technologies in mass spectrometry and nuclear magnetic resonance spectroscopy, hundreds to thousands of metabolites can now be quantitatively measured from minimal amounts of biological material. This has thereby enabled in-depth insight into the metabolism of living organisms and the biochemistry of their environment. Metabolite profiling, or metabolomics, has become a powerful approach that has been widely adopted in many areas and is by now a solid pillar next to genomics, proteomics and transcriptomics. Yet, the comprehensive integration of metabolomics data with other ‘omics’ is still in the early developmental phase. However, environmental metabolomics should now step up and deliver profound data on the complexity, variability and plasticity of the environment and natural populations to build a basis for future research directions. An expansion towards cells and organisms from diverse environments will without doubt increase the current metabolome inventory and tasks should be taken to implement such data into current or future databases including tools to help annotate so far undescribed metabolites. Here, high throughput and robust analytical tools are needed to deliver accurate metabolic profiling data. Due to the enormous improvements in mass-spectrometry technologies, possibilities like mass-spectrometry imaging should be used increasingly to also give spatial information to certain metabolites of interest.
In this Special Issue of Metabolites, original papers, which are describing novel metabolomics methods for the diverse nature of environmental samples from the terrestrial to the marine realm, are welcome. Work which shows new directions of metabolomics applied to monitor environmental factors (abiotic or biotic) towards populations of organisms is of interest for this Special Issue. Comprehensive descriptions of metabolome data, either from extracts or via direct MS imaging studies are welcome here. Manuscripts dealing with other challenging issues in the environmental metabolomics field including software tools and databases for metabolite annotation or combination with other –omics are also highly welcome.
Dr. Manuel Liebeke
Relevant special issue can be found here: http://www.mdpi.com/journal/metabolites/special_issues/stress-metabolism.
- Environmental stressors of metabolism and stress responses
- Mass spectrometry and NMR methods for high content analysis
- Bioinformatic tools for metabolite assignment and data analysis (e.g. multi-omics)