Special Issue "Nanomaterials for Biomedical Applications"
A special issue of Materials (ISSN 1996-1944).
Deadline for manuscript submissions: 9 April 2018
Prof. Dr. Anne Marie Healy
Pharmaceutics and Pharmaceutical Technology, School of Pharmacy and Pharmaceutical Sciences, Trinity College Dublin, the University of Dublin, Dublin 2, Ireland
Website | E-Mail
Interests: pharmaceutical material science; preformulation and formulation of pharmaceuticals; amorphous solids; co-crystals; formulating poorly soluble drugs; pharmaceutical processing; pulmonary drug delivery and formulation stability
Assist. Prof. Eduardo Ruiz-Hernandez
Nanomaterials have recently become one of the most active research fields in the areas of engineering, chemistry, solid state physics, biotechnology and biomedicine. One reason for this interest is that nanomaterials display novel and often enhanced properties compared to traditional materials, which opens up the potential for new technological applications. The use of nanomaterials in the biomedical field presents many revolutionary opportunities in the fight against all kinds of cancer, cardiac and neurodegenerative disorders, infection and other diseases. The nanoparticle platforms that have been extensively explored for biomedical applications are predominantly either purely inorganic or organic materials. For example organic nanomaterials such as nanocrystals, liposomes, dendrimers, hyper-branched organic polymers, micelles and polymeric hydrogel nanoparticles have been widely used as imaging and therapeutic agents. Recently, inorganic nanomaterials such as quantum dots, superparamagnetic iron oxide nanoparticles, metallic nanoparticles and metal oxides have also attracted great attention for biomedical applications.
In another relevant example, hybrid nanoparticles are composed of both inorganic and organic components that can not only retain the beneficial features of both inorganic and organic nanomaterials, but also possess unique advantages over the other two types. For instance, the ability to combine a multitude of organic and inorganic components in a modular fashion allows for systematic tuning of the properties for biomedical applications. Hybrid nanoparticles have been proposed for the targeted release of diagnostic agents and drugs, and even as stimuli responsive nanocarriers to enhance therapy selectivity. The combination of these materials with current efforts to identify genes, proteins and metabolites implicated in human disease and use system biology approaches to develop new prognostic tools and more targeted therapies for patients, will dramatically impact healthcare in the coming years.
This Special Issue focuses on the use of organic/inorganic or hybrid nanomaterials for biomedical applications. We invite full papers, communications and reviews covering one or several of the topics included in (or related to) the keywords below.
Prof. Dr. Anne Marie Healy
Asstis. Prof. Eduardo Ruiz-Hernandez
Asstit. Prof. Juan Luis Vivero-Escoto
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Materials is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
nanoparticle manufacture and processing
The below list represents only planned manuscripts. Some of these manuscripts have not been received by the Editorial Office yet. Papers submitted to MDPI journals are subject to peer-review.
Article type: Review
Title: Local chemotherapy drug delivery systems for the treatment of glioblastoma multiforme
Authors: Eduardo Ruiz-Hernandez et al.
Title: The Role of Mucin in the Toxicological Impact of Polystyrene Nanoparticles
Authors: Iwona Inkielewicz-Stepniak 1, Lidia Tajber 2, Marek W Radomski 3, Carlos Medina 2,4 and Maria J. Santos-Martinez 2,4,5
Affiliation: 1 Department of Medical Chemistry, Medical University of Gdansk, Poland
2 School of Pharmacy and Pharmaceutical Sciences, Trinity College Dublin, the University of Dublin, Dublin 2, Ireland
3 College of Medicine, University of Saskatchewan, Canada
4 Trinity Biomedical Sciences Institute, Trinity College Dublin, the University of Dublin, Dublin 2, Ireland
5 School of Medicine, Trinity College Dublin, the University of Dublin, Dublin 2, Ireland
Authors: Peipei Zhang 1 and Chelsea Ryan Virgile 2
Affiliations: 1 Beijing Aerospace University
2 University of Maryland College Park
Abstract: Nanomaterials have shown great potentials in biomedical applications. Most nanomaterials are generated via bottom-up technologies—techniques that assemble nanomaterials from small building blocks such as chemical molecules. These methods, while useful by producing nanomaterials in a large batch, have very limited flexibility in controlling materials properties such as size, surface property, cargo loading, etc. As a contrast, advanced manufacturing techniques such as photolithography, soft lithography and layer-by-layer assembly allows fabricating nanomaterials with highly controllable features, enabling unique translational studies and applications. Here in this work, we will review the existing technologies that employ advanced manufacturing techniques for generating nanomaterials with precisely defined characteristics, as well as their translational application. We will also address the advantages of these highly controlled nanomaterials as compared to conventional materials in biomedical applications.
Title: Nanoparticles for sensing and medical diagnostic applications
Authors: Luigi La Spada et al.
Abstract: A modeling and design approach is proposed for nanoparticle-based electromagnetic devices. First, the structure properties will be analytically studied by using classical electromagnetic theory based on Maxwell’s equations. The proposed model provides us the possibility to correlate the nanoparticle electromagnetic properties (amplitude, phase and bandwidth) with its geometrical characteristics (shape, geometry, dimensions) Secondly, new designs based on “metamaterial” concept are proposed, demonstrating great performances in terms of wide-angle range functionality, multi-band and wide-band behavior, compared to conventional devices working at the same frequencies. The approach offers potential applications to build-up new advanced platforms for sensing and medical diagnostics. Therefore, in the third and final part of the article some practical examples will be reported such as cancer detection, water content measurements and chemical analysis (glucose concentration measurements and blood diseases monitoring).