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Materials 2018, 11(1), 109; https://doi.org/10.3390/ma11010109

Nitrogen-Doped Diamond Film for Optical Investigation of Hemoglobin Concentration

1
Department of Metrology and Optoelectronics, Faculty of Electronics, Telecommunications and Informatics, Gdansk University of Technology, 80-233 Gdansk, Poland
2
Institute for Materials Research (IMO), Hasselt University, B-3590 Diepenbeek, Belgium
3
IMOMEC, IMEC vzw, B-3590 Diepenbeek, Belgium
4
Department of Optoelectronics, Faculty of Electrical Engineering, Silesian University of Technology, 44-100 Gliwice, Poland
5
Department of Morphological Sciences, Faculty of Veterinary Medicine, Warsaw University of Life Sciences, 02-776 Warszawa, Poland
*
Authors to whom correspondence should be addressed.
Received: 28 November 2017 / Revised: 21 December 2017 / Accepted: 9 January 2018 / Published: 11 January 2018
(This article belongs to the Special Issue Nanomaterials for Biomedical Applications)
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Abstract

In this work we present the fabrication and characterization of a diamond film which can be utilized in the construction of optical sensors for the investigation of biological samples. We produced a nitrogen-doped diamond (NDD) film using a microwave plasma enhanced chemical vapor deposition (MWPECVD) system. The NDD film was investigated with the use of scanning electron microscopy (SEM), atomic force microscopy (AFM) and Raman spectroscopy. The NDD film was used in the construction of the fiber optic sensor. This sensor is based on the Fabry–Pérot interferometer working in a reflective mode and the NDD film is utilized as a reflective layer of this interferometer. Application of the NDD film allowed us to obtain the sensor of hemoglobin concentration with linear work characteristics with a correlation coefficient (R2) equal to 0.988. View Full-Text
Keywords: nitrogen-doped diamond; fiber optic sensor; interferometer; hemoglobin; Fabry–Pérot sensor; biophotnic sensor nitrogen-doped diamond; fiber optic sensor; interferometer; hemoglobin; Fabry–Pérot sensor; biophotnic sensor
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Majchrowicz, D.; Kosowska, M.; Sankaran, K.J.; Struk, P.; Wąsowicz, M.; Sobaszek, M.; Haenen, K.; Jędrzejewska-Szczerska, M. Nitrogen-Doped Diamond Film for Optical Investigation of Hemoglobin Concentration. Materials 2018, 11, 109.

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