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Special Issue "Marine Chitin"

A special issue of Marine Drugs (ISSN 1660-3397).

Deadline for manuscript submissions: 31 March 2018

Special Issue Editors

Guest Editor
Dr. Hitoshi Sashiwa

Kaneka Co., Ltd, 5-1-1 Torikai-Nishi, Settsu, Osaka 566-0072 Japan
Website | E-Mail
Phone: +81-72-653-8333
Interests: chemical modification of chitin and chitosan and their biomedical applications
Guest Editor
Prof. Dr. David Harding

Institute of Fundamental Sciences, Massey University, Private Bag 11 222, Palmerston North, 4442, New Zealand
Website | E-Mail
Phone: +6421767565
Interests: hydrogels and other biopolymers

Special Issue Information

Dear Colleagues,

As a result of our call in 2017 for submissions to a Special Issue, Advances in Marine Chitin and Chitosan II, 2017, in Marine Drugs, we are now pleased to tell you that this issue has been published. Over twenty high class papers were included in this issue, which we now plan to publish as a book. In addition we now seek to publish a further Special Issue, Marine Chitin, 2018, in Marine Drugs. As before, we plan to produce a strong, very exciting issue that will encompass breakthroughs in high value, scientific and industrial chitin and chitosan research. Despite significant advances in chitin and chitosan research since the 1970s, current overviews in recent publications involving chitin and chitosan research advances need reporting.

We look forward very much to your input.

Dr. Hitoshi Sashiwa
Prof. Dr. David Harding
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Marine Drugs is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • chitin
  • chitosan
  • chito-oligosaccharide
  • glucosamine
  • N-acetyl-D-glucosamine
  • chemical modification
  • controlled drug delivery
  • hydrogels
  • tissue engineering
  • nanomaterial

Published Papers (2 papers)

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Research

Open AccessArticle Preparation and Characterization of Chitosan Obtained from Shells of Shrimp (Litopenaeus vannamei Boone)
Mar. Drugs 2017, 15(5), 141; doi:10.3390/md15050141
Received: 5 April 2017 / Revised: 3 May 2017 / Accepted: 8 May 2017 / Published: 15 May 2017
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Abstract
The main source of commercial chitosan is the extensive deacetylation of its parent polymer chitin. It is present in green algae, the cell walls or fungi and in the exoskeleton of crustaceans. A novel procedure for preparing chitosan from shrimp shells was developed.
[...] Read more.
The main source of commercial chitosan is the extensive deacetylation of its parent polymer chitin. It is present in green algae, the cell walls or fungi and in the exoskeleton of crustaceans. A novel procedure for preparing chitosan from shrimp shells was developed. The procedure involves two 10-minutes bleaching steps with ethanol after the usual demineralization and deproteinization processes. Before deacetylation, chitin was immersed in 12.5 M NaOH, cooled down and kept frozen for 24 h. The obtained chitosan was characterized using scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FTIR), UV, X-ray diffraction (XRD) and viscosimetry. Samples of white chitosan with acetylation degrees below 9 % were obtained, as determined by FTIR and UV-first derivative spectroscopy. The change in the morphology of samples was followed by SEM. The ash content of chitosan samples were all below 0.063 % . Chitosan was soluble in 1 % acetic acid with insoluble contents of 0.62 % or less. XRD patterns exhibited the characteristic peaks of chitosan centered at 10 and 20 degrees in 2 θ . The molecular weight of chitosan was between 2.3 and 2.8 × 10 5 g/mol. It is concluded that the procedure developed in the present work allowed obtaining chitosans with physical and chemical properties suitable for pharmaceutical applications. Full article
(This article belongs to the Special Issue Marine Chitin)
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Figure 1

Open AccessArticle Bioresponsive Materials for Drug Delivery Based on Carboxymethyl Chitosan/Poly(γ-Glutamic Acid) Composite Microparticles
Mar. Drugs 2017, 15(5), 127; doi:10.3390/md15050127
Received: 27 March 2017 / Revised: 14 April 2017 / Accepted: 17 April 2017 / Published: 28 April 2017
PDF Full-text (11958 KB) | HTML Full-text | XML Full-text | Supplementary Files
Abstract
Carboxymethyl chitosan (CMCS) microparticles are a potential candidate for hemostatic wound dressing. However, its low swelling property limits its hemostatic performance. Poly(γ-glutamic acid) (PGA) is a natural polymer with excellent hydrophilicity. In the current study, a novel CMCS/PGA composite microparticles with a dual-network
[...] Read more.
Carboxymethyl chitosan (CMCS) microparticles are a potential candidate for hemostatic wound dressing. However, its low swelling property limits its hemostatic performance. Poly(γ-glutamic acid) (PGA) is a natural polymer with excellent hydrophilicity. In the current study, a novel CMCS/PGA composite microparticles with a dual-network structure was prepared by the emulsification/internal gelation method. The structure and thermal stability of the composite were determined by Fourier transform infrared spectroscopy (FTIR), X-ray powder diffraction (XRD), scanning electron microscope (SEM), X-ray photoelectron spectroscopy (XPS), and thermogravimetric analysis (TGA). The effects of preparation conditions on the swelling behavior of the composite were investigated. The results indicate that the swelling property of CMCS/PGA composite microparticles is pH sensitive. Levofloxacin (LFX) was immobilized in the composite microparticles as a model drug to evaluate the drug delivery performance of the composite. The release kinetics of LFX from the composite microparticles with different structures was determined. The results suggest that the CMCS/PGA composite microparticles are an excellent candidate carrier for drug delivery. Full article
(This article belongs to the Special Issue Marine Chitin)
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