Special Issue "miRNA Regulation"
A special issue of Genes (ISSN 2073-4425).
Deadline for manuscript submissions: closed (30 June 2014)
Dr. Louise Torp Dalgaard
Eukaryot Cellebiologi, The Department of Science, Systems and Models, Roskilde University, Universitetsvej 1, 18.2, DK-4000, Roskilde, Denmark
Interests: MicroRNA; glucose homestasis; beta-cell biology; genetics; diabetes mellitus; transcriptional regulation
The field of microRNA biology is growing with exponential speed. Since the first microRNA was identified in 1993 by Victor Ambros and colleagues (the lin-4 heterochronic gene in C. Elegans), more than 24,000 microRNAs have now been identified. MicroRNAs constitute a pervasive post-transcriptional filter on protein or mRNA expression levels that are likely to control developmental timing, cellular differentiation, stress responses, metabolism and proliferation. However, the role of microRNA in mammalian tissue development and differentiation is still quite uncharacterized. Therefore, it is important to describe their mechanisms of actions, expression patterns and possible target genes and cellular pathways with which they interact. This Special Issue of "Genes" seeks reviews and original papers covering a wide range of topics related to microRNA biology, such as regulation of expression in various disorders (cancer, metabolism, autoimmunity to mention but a few), genetics of microRNAs and their target sites, functional analysis of microRNA function and studies of interactions between microRNAs and target genes.
Dr. Louise Dalgaard
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Genes is an international peer-reviewed Open Access monthly journal published by MDPI.
- microRNAs and
- developmental timing
- cellular differentiation
- target genes
- cancer, metabolism and diabetes, autoimmunity, aging
- expression patterns
- biomarker identification