Special Issue "Cellular Stress Response"

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A special issue of Cells (ISSN 2073-4409).

Deadline for manuscript submissions: closed (31 July 2012)

Special Issue Editor

Guest Editor
Dr. Alex Almasan
Department of Cancer Biology, Bridge appointment with Department of Radiation Oncology, Taussig Cancer Institute, Lerner Research Institute / NB40, 9500 Euclid Avenue, Cleveland, OH 44195, USA
Website: http://www.lerner.ccf.org/cancerbio/almasan/
E-Mail: almasaa@ccf.org
Interests: apoptosis; autophagy; cancer (leukemia and prostate); cell death; cell cycle; DNA damage and repair

Special Issue Information

Dear Colleagues,

Cells are constantly subjected to various forms of endogenous and exogenous stress that shapes their existence. How they respond to it depends on exogenous factors and their ability to handle the stress to which they are exposed.   Examples of cellular stress are the DNA damage caused by radiation, chemotherapy, hypoxia, oncogene activation; these will ultimately lead to transient or permanent (senescence) growth arrest, or if the damage is severe, death that ultimately eliminates the damaged cells . Whether cells mount a protective response or succumb to death depends to a large extent on the nature and duration of the stress and the particular cell type. How such cellular stress leads to activation of pro-survival molecules that may activate repair of DNA damage in the nucleus or in the cytoplasm by autophagy (see dedicated special issue) and/or prevent cell death is of considerable interest. Moreover, alternative splicing and the adaptive response are of special interest.

This Special Issue offers an Open Access forum that aims at bringing together a collection of original research and review articles addressing recent developments in the cellular stress response, the signaling pathways that mitigate its biological effects and the ensuing cell proliferation and/or survival outcomes.

Dr. Alex Almasan
Guest Editor

Keywords

  • Adaptation
  • Autophagy
  • Cell cycle arrest
  • Cellular stress
  • DNA repair
  • Genotoxic stress
  • Hypoxia
  • Oncogene activation
  • Oxidative stress
  • Programmed cell death
  • Senescence

Published Papers (11 papers)

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Displaying article 1-11
p. 224-243
by , ,  and
Cells 2013, 2(2), 224-243; doi:10.3390/cells2020224
Received: 28 February 2013; in revised form: 29 March 2013 / Accepted: 2 April 2013 / Published: 10 April 2013
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(This article belongs to the Special Issue Cellular Stress Response)
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p. 1197-1224
by ,  and
Cells 2012, 1(4), 1197-1224; doi:10.3390/cells1041197
Received: 2 September 2012; in revised form: 6 November 2012 / Accepted: 7 November 2012 / Published: 10 December 2012
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(This article belongs to the Special Issue Cellular Stress Response)
p. 1089-1106
by , , , ,  and
Cells 2012, 1(4), 1089-1106; doi:10.3390/cells1041089
Received: 1 August 2012; in revised form: 9 November 2012 / Accepted: 9 November 2012 / Published: 13 November 2012
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(This article belongs to the Special Issue Cellular Stress Response)
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p. 976-993
by , , ,  and
Cells 2012, 1(4), 976-993; doi:10.3390/cells1040976
Received: 28 September 2012; in revised form: 26 October 2012 / Accepted: 31 October 2012 / Published: 5 November 2012
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(This article belongs to the Special Issue Cellular Stress Response)
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p. 926-950
by
Cells 2012, 1(4), 926-950; doi:10.3390/cells1040926
Received: 17 September 2012; in revised form: 15 October 2012 / Accepted: 22 October 2012 / Published: 1 November 2012
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(This article belongs to the Special Issue Cellular Stress Response)
p. 738-753
by  and
Cells 2012, 1(4), 738-753; doi:10.3390/cells1040738
Received: 10 August 2012; Accepted: 25 September 2012 / Published: 15 October 2012
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(This article belongs to the Special Issue Cellular Stress Response)
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p. 774-798
by ,  and
Cells 2012, 1(4), 774-798; doi:10.3390/cells1040774
Received: 12 September 2012; in revised form: 28 September 2012 / Accepted: 1 October 2012 / Published: 15 October 2012
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(This article belongs to the Special Issue Cellular Stress Response)
p. 799-831
by , ,  and
Cells 2012, 1(4), 799-831; doi:10.3390/cells1040799
Received: 6 August 2012; in revised form: 29 September 2012 / Accepted: 30 September 2012 / Published: 15 October 2012
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(This article belongs to the Special Issue Cellular Stress Response)
p. 711-737
by , ,  and
Cells 2012, 1(4), 711-737; doi:10.3390/cells1040711
Received: 31 July 2012; in revised form: 14 September 2012 / Accepted: 27 September 2012 / Published: 10 October 2012
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(This article belongs to the Special Issue Cellular Stress Response)
p. 646-666
by  and
Cells 2012, 1(3), 646-666; doi:10.3390/cells1030646
Received: 1 August 2012; in revised form: 24 August 2012 / Accepted: 27 August 2012 / Published: 11 September 2012
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(This article belongs to the Special Issue Cellular Stress Response)
p. 631-645
by  and
Cells 2012, 1(3), 631-645; doi:10.3390/cells1030631
Received: 24 July 2012; in revised form: 2 August 2012 / Accepted: 20 August 2012 / Published: 30 August 2012
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Last update: 25 February 2014

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