Stem Cell Transplantation in Cancer Treatment
A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Cancer Therapy".
Deadline for manuscript submissions: closed (10 April 2021) | Viewed by 35230
Special Issue Editors
Interests: hematopoietic stem cell transplantation; pediatric AML; pediatric MDS; cancer predisposing syndromes; gut microbiome; cellular therapies; pediatric hematology/oncology
Special Issues, Collections and Topics in MDPI journals
Interests: Hematopoietic stem cell transplantation; Acute lymphoblastic leukemia; Acute myeloid leukemia; Acute promyelocytic leukemia; Inherited bone marrow failure syndromes; Hemoglobinopathies
Special Issue Information
Dear Colleagues,
Stem cell transplantation (SCT) is currently universally established as a curative treatment option for many hematologic malignancies, as well as other neoplastic disorders.
Although this procedure was originally conceived more than 60 years ago as a treatment to rescue victims of accidental irradiation exposure, over the years the immunotherapeutic potential of SCT has been progressively discovered and exploited, marking a progressive transition of this technique from an experimental strategy to an ideal platform to explore a cellular-based anti-cancer approach.
The dramatic progress achieved over the last three decades in the field of HLA-matching techniques, conditioning regimens, graft manipulation, graft-versus-host disease prophylaxis, supportive care, and modulation of immunological complications led to a broad expansion of the clinical use of SCT, and indications for this procedure are becoming transversal and rapidly evolving. Moreover, research on the use of stem cells and mature reactive T-cells, which is now revolutionizing the scenario of cancer treatment, sinks its roots and moved its development starting from SCT.
This Special Issue will highlight the role of SCT in the challenging scenario of cancer treatment, covering both basic research and more clinical aspects that may advance our understanding of this intriguing procedure.
Dr. Riccardo Masetti
Dr. Luisa Strocchio
Guest Editors
Manuscript Submission Information
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Keywords
- Hematopoietic stem cell transplantation
- Cancer
- Hematological malignancies
- Leukemia
- Lymphoma
- Immunotherapy