Special Issue "Role of Oxidatively-Induced DNA Damage in Carcinogenesis"
A special issue of Cancers (ISSN 2072-6694).
Deadline for manuscript submissions: closed (15 April 2014)
Prof. Dr. Alexandros G. Georgakilas
DNA Damage Laboratory, Physics Department, School of Applied Mathematical and Physical Sciences, National Technical University of Athens, Zografou Campus, 15780 Athens, Greece
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Fax: +30 210 772 3025
Interests: radiation biology; cancer biology; DNA damage and repair; oxidative stress; carcinogenesis
Oxidative stress and all related effects in the cell like protein and DNA damage, mutagenesis, inactivation of DNA damage response pathways, epigenetic changes and further more importantly genomic instability and malignant transformation have gained through the years an increased attention. It is of great necessity to clarify and underline the significance and ‘real’ relevance of oxidatively-induced DNA damage in the initiation of carcinogenesis.
We would like to invite manuscripts that aim to elucidate the role(s) of oxidative stress related DNA damage of all forms in carcinogenesis and for various types of cancers like breast, brain, lung, prostate etc. We are particularly interested in manuscripts deciphering the mechanisms and pathways that oxidative DNA damage can lead to mutation and inactivation of DNA repair and apoptotic genes and epigenetic changes and new therapy tools. We are also welcome manuscripts focusing on the synergistic effects between inflammation, oxidative stress and tumorigenesis in humans and to potential anti-oxidant and anti-inflammatory pathways that reduce cancer risk. By devoting a special issue just on oxidative stress-related carcinogenesis, we hope to join forces and enhance the knowledge in the specific field and above all promote the new era of therapeutic discoveries targeting cancer through the diminution of oxidative stress and inflammation.
Dr. Alexandros Georgakilas
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- oxidative stress
- DNA damage
- DNA repair inactivation
- DNA damage response
- genomic instability
- antioxidant therapies