Special Issue "Ethanol Neurotoxicity"
A special issue of Brain Sciences (ISSN 2076-3425).
Deadline for manuscript submissions: closed (28 February 2013)
Dr. D. Blaine Moore
Department of Biology, Kalamazoo College, Kalamazoo, MI 49006, USA
Phone: +269 337 7301
Fax: +269 337 7508
Interests: ethanol toxicity mechanism; particularly the role of Bcl-2 family members and caspases
Alcohol abuse is a worldwide public health concern resulting in significant morbidity, mortality and financial burden. Decades of research have pinpointed the pathological consequences of ethanol and have focused considerable attention on neurotoxicity. Indeed, ethanol is known to induce structural changes and neuronal cell death in the nervous system of humans and animals, and significant progress is being made in unraveling the mechanisms and neural consequences of ethanol exposure. Several important questions related to ethanol neurotoxicity remain unanswered: What is the precise cellular mechanism of ethanol induced neuronal cell death? What is the role of support cells such as glia in neurotoxicity, and are glia themselves targets of ethanol? What are the developmental consequences of ethanol exposure culminating in Fetal Alcohol Spectrum Disorders (FASD)? How does ethanol affect neuronal membrane proteins such as receptors and transporters? Are synaptic connections between neurons affected by ethanol? What are the pathological consequences of long-term ethanol exposure in alcoholics? What structural changes are noted in brain imaging studies of chronic alcoholics or children with FASD?
This special issue will collect a series of articles which document the important strides being made towards understanding the basis for and consequences of ethanol neurotoxicity. It is meant to be inclusive of the major questions indicated above, and it is my hope that the ethanol research community will greatly benefit from this anthology.
Dr. D. Blaine Moore
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Brain Sciences is an international peer-reviewed Open Access quarterly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 600 CHF (Swiss Francs). English correction and/or formatting fees of 250 CHF (Swiss Francs) will be charged in certain cases for those articles accepted for publication that require extensive additional formatting and/or English corrections.
- ethanol-induced neuronal apoptosis
- fetal alcohol spectrum disorder
- ethanol and membrane proteins
- ethanol and signal transduction
- ethanol and glia
- ethanol and synapses/circuitry
- neuropathology in chronic alcoholism
- ethanol and neuro-imaging
- ethanol and cognition